Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM033702-02
Application #
3283619
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1984-09-14
Project End
1987-08-31
Budget Start
1985-09-01
Budget End
1986-08-31
Support Year
2
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Chicago
Department
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Yu, Huijun; Chan, Yuen-Ling; Wool, Ira G (2009) The identification of the determinants of the cyclic, sequential binding of elongation factors tu and g to the ribosome. J Mol Biol 386:802-13
Chan, Yuen-Ling; Wool, Ira G (2008) The integrity of the sarcin/ricin domain of 23 S ribosomal RNA is not required for elongation factor-independent peptide synthesis. J Mol Biol 378:12-9
Chan, Yuen-Ling; Dresios, John; Wool, Ira G (2006) A pathway for the transmission of allosteric signals in the ribosome through a network of RNA tertiary interactions. J Mol Biol 355:1014-25
Dresios, John; Chan, Yuen-Ling; Wool, Ira G (2006) Determination of the amino acids in yeast ribosomal protein YS11 essential for the recognition of nucleotides in 18 S ribosomal RNA. J Biol Chem 281:13478-84
Dresios, John; Chan, Yuen-Ling; Wool, Ira G (2005) A determination of the identity elements in yeast 18 S ribosomal RNA for the recognition of ribosomal protein YS11: the role of the kink-turn motif in helix 11. J Mol Biol 345:681-93
Chan, Yuen-Ling; Correll, Carl C; Wool, Ira G (2004) The location and the significance of a cross-link between the sarcin/ricin domain of ribosomal RNA and the elongation factor-G. J Mol Biol 337:263-72
Gluck, Anton; Wool, Ira G (2002) Analysis by systematic deletion of amino acids of the action of the ribotoxin restrictocin. Biochim Biophys Acta 1594:115-26
Dresios, John; Chan, Yuen-Ling; Wool, Ira G (2002) The role of the zinc finger motif and of the residues at the amino terminus in the function of yeast ribosomal protein YL37a. J Mol Biol 316:475-88
Chan, Y L; Sitikov, A S; Wool, I G (2000) The phenotype of mutations of the base-pair C2658.G2663 that closes the tetraloop in the sarcin/ricin domain of Escherichia coli 23 S ribosomal RNA. J Mol Biol 298:795-805
Macbeth, M R; Wool, I G (1999) Characterization of in vitro and in vivo mutations in non-conserved nucleotides in the ribosomal RNA recognition domain for the ribotoxins ricin and sarcin and the translation elongation factors. J Mol Biol 285:567-80

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