Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM033783-13
Application #
2177143
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1984-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Santa Barbara
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
Santa Barbara
State
CA
Country
United States
Zip Code
93106
Irelan, J T; Gutkin, G I; Clarke, L (2001) Functional redundancies, distinct localizations and interactions among three fission yeast homologs of centromere protein-B. Genetics 157:1191-203
Baum, M; Clarke, L (2000) Fission yeast homologs of human CENP-B have redundant functions affecting cell growth and chromosome segregation. Mol Cell Biol 20:2852-64
Halverson, D; Gutkin, G; Clarke, L (2000) A novel member of the Swi6p family of fission yeast chromo domain-containing proteins associates with the centromere in vivo and affects chromosome segregation. Mol Gen Genet 264:492-505
Zebarjadian, Y; King, T; Fournier, M J et al. (1999) Point mutations in yeast CBF5 can abolish in vivo pseudouridylation of rRNA. Mol Cell Biol 19:7461-72
Halverson, D; Baum, M; Stryker, J et al. (1997) A centromere DNA-binding protein from fission yeast affects chromosome segregation and has homology to human CENP-B. J Cell Biol 136:487-500
Ngan, V K; Clarke, L (1997) The centromere enhancer mediates centromere activation in Schizosaccharomyces pombe. Mol Cell Biol 17:3305-14
Marschall, L G; Clarke, L (1995) A novel cis-acting centromeric DNA element affects S. pombe centromeric chromatin structure at a distance. J Cell Biol 128:445-54
Smith, J G; Caddle, M S; Bulboaca, G H et al. (1995) Replication of centromere II of Schizosaccharomyces pombe. Mol Cell Biol 15:5165-72
Baum, M; Ngan, V K; Clarke, L (1994) The centromeric K-type repeat and the central core are together sufficient to establish a functional Schizosaccharomyces pombe centromere. Mol Biol Cell 5:747-61
Steiner, N C; Clarke, L (1994) A novel epigenetic effect can alter centromere function in fission yeast. Cell 79:865-74

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