Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM033928-05S1
Application #
3284123
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1985-01-01
Project End
1990-03-31
Budget Start
1989-12-01
Budget End
1990-03-31
Support Year
5
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Brown University
Department
Type
Schools of Medicine
DUNS #
001785542
City
Providence
State
RI
Country
United States
Zip Code
02912
Laxmikanthan, Gurunathan; Xu, Chen; Brilot, Axel F et al. (2016) Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction. Elife 5:
Landy, Arthur (2015) The ? Integrase Site-specific Recombination Pathway. Microbiol Spectr 3:MDNA3-0051-2014
Tong, Wenjun; Warren, David; Seah, Nicole E et al. (2014) Mapping the ? Integrase bridges in the nucleoprotein Holliday junction intermediates of viral integrative and excisive recombination. Proc Natl Acad Sci U S A 111:12366-71
Seah, Nicole E; Warren, David; Tong, Wenjun et al. (2014) Nucleoprotein architectures regulating the directionality of viral integration and excision. Proc Natl Acad Sci U S A 111:12372-7
Matovina, Mihaela; Seah, Nicole; Hamilton, Theron et al. (2010) Stoichiometric incorporation of base substitutions at specific sites in supercoiled DNA and supercoiled recombination intermediates. Nucleic Acids Res 38:e175
Warren, David; Laxmikanthan, Gurunathan; Landy, Arthur (2008) A chimeric Cre recombinase with regulated directionality. Proc Natl Acad Sci U S A 105:18278-83
Hazelbaker, Dane; Azaro, Marco A; Landy, Arthur (2008) A biotin interference assay highlights two different asymmetric interaction profiles for lambda integrase arm-type binding sites in integrative versus excisive recombination. J Biol Chem 283:12402-14
Sun, Xingmin; Mierke, Dale F; Biswas, Tapan et al. (2006) Architecture of the 99 bp DNA-six-protein regulatory complex of the lambda att site. Mol Cell 24:569-80
Mumm, Jeffrey P; Landy, Arthur; Gelles, Jeff (2006) Viewing single lambda site-specific recombination events from start to finish. EMBO J 25:4586-95
Radman-Livaja, Marta; Biswas, Tapan; Ellenberger, Tom et al. (2006) DNA arms do the legwork to ensure the directionality of lambda site-specific recombination. Curr Opin Struct Biol 16:42-50

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