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Oviatt, Alexandria A; Kuriappan, Jissy A; Minniti, Elirosa et al. (2018) Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase II? and II?. Bioorg Med Chem Lett 28:2961-2968
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Dahlman, Kimberly Brown; Weinger, Matthew B; Lomis, Kimberly D et al. (2018) Integrating Foundational Sciences in a Clinical Context in the Post-Clerkship Curriculum. Med Sci Educ 28:145-154
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Niederhoffer, Eric C; Cline, Susan D; Osheroff, Neil et al. (2017) Teaching Biochemistry and Genetics to Students of Dentistry, Medicine, and Pharmacy 6th International Conference of the Association of Biochemistry Educators (ABE) Clearwater Beach, FL, USA, May 7-11, 2017. Med Sci Educ 27:855-859
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Ashley, Rachel E; Dittmore, Andrew; McPherson, Sylvia A et al. (2017) Activities of gyrase and topoisomerase IV on positively supercoiled DNA. Nucleic Acids Res 45:9611-9624
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Ashley, Rachel E; Lindsey Jr, R Hunter; McPherson, Sylvia A et al. (2017) Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance. Biochemistry 56:4191-4200
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Minniti, Elirosa; Byl, Jo Ann W; Riccardi, Laura et al. (2017) Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase II?. Bioorg Med Chem Lett 27:4687-4693
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Infante Lara, Lorena; Sledge, Alexis; Laradji, Amine et al. (2017) Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-ones act as covalent poisons of human topoisomerase II?. Bioorg Med Chem Lett 27:586-589
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Kristoffersen, Emil L; Givskov, Asger; Jørgensen, Line A et al. (2017) Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events. Nucleic Acids Res 45:7855-7869
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Yu, Xiang; Davenport, James W; Urtishak, Karen A et al. (2017) Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci. Genome Res 27:1238-1249
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Ashley, Rachel E; Blower, Tim R; Berger, James M et al. (2017) Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase. Biochemistry 56:5440-5448
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