Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM033956-12
Application #
2177206
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1985-03-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Biology
Type
Schools of Dentistry
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Francia, Maria Victoria; Weaver, Keith E; Goicoechea, Patricia et al. (2007) Characterization of an active partition system for the Enterococcus faecalis pheromone-responding plasmid pAD1. J Bacteriol 189:8546-55
Clewell, Don B (2007) Properties of Enterococcus faecalis plasmid pAD1, a member of a widely disseminated family of pheromone-responding, conjugative, virulence elements encoding cytolysin. Plasmid 58:205-27
Ozawa, Yoshiyuki; De Boever, Erika H; Clewell, Don B (2005) Enterococcus faecalis sex pheromone plasmid pAM373: analyses of TraA and evidence for its interaction with RpoB. Plasmid 54:57-69
Sedgley, C M; Molander, A; Flannagan, S E et al. (2005) Virulence, phenotype and genotype characteristics of endodontic Enterococcus spp. Oral Microbiol Immunol 20:10-9
Sedgley, C M; Nagel, A C; Shelburne, C E et al. (2005) Quantitative real-time PCR detection of oral Enterococcus faecalis in humans. Arch Oral Biol 50:575-83
Sedgley, C M; Lennan, S L; Clewell, D B (2004) Prevalence, phenotype and genotype of oral enterococci. Oral Microbiol Immunol 19:95-101
Francia, Maria Victoria; Fujimoto, Shuhei; Tille, Patricia et al. (2004) Replication of Enterococcus faecalis pheromone-responding plasmid pAD1: location of the minimal replicon and oriV site and RepA involvement in initiation of replication. J Bacteriol 186:5003-16
Flannagan, Susan E; Chow, Joseph W; Donabedian, Susan M et al. (2003) Plasmid content of a vancomycin-resistant Enterococcus faecalis isolate from a patient also colonized by Staphylococcus aureus with a VanA phenotype. Antimicrob Agents Chemother 47:3954-9
Clewell, Don B; Francia, M Victoria; Flannagan, Susan E et al. (2002) Enterococcal plasmid transfer: sex pheromones, transfer origins, relaxases, and the Staphylococcus aureus issue. Plasmid 48:193-201
Francia, M Victoria; Clewell, Don B (2002) Transfer origins in the conjugative Enterococcus faecalis plasmids pAD1 and pAM373: identification of the pAD1 nic site, a specific relaxase and a possible TraG-like protein. Mol Microbiol 45:375-95

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