Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM034190-17
Application #
2177329
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1978-04-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cornell University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Liachko, Ivan; Tye, Bik K (2005) Mcm10 is required for the maintenance of transcriptional silencing in Saccharomyces cerevisiae. Genetics 171:503-15
Douglas, Nancy L; Dozier, Samantha K; Donato, Justin J (2005) Dual roles for Mcm10 in DNA replication initiation and silencing at the mating-type loci. Mol Biol Rep 32:197-204
Chang, Victoria K; Donato, Justin J; Chan, Clarence S et al. (2004) Mcm1 promotes replication initiation by binding specific elements at replication origins. Mol Cell Biol 24:6514-24
Tye, Bik K; Chang, Victoria K (2004) Dual functional regulators coordinate DNA replication and gene expression in proliferating cells. Front Biosci 9:2548-55
Sawyer, Sara L; Cheng, Irene H; Chai, Weihang et al. (2004) Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae. J Mol Biol 340:195-202
Fitch, Michael J; Donato, Justin J; Tye, Bik K (2003) Mcm7, a subunit of the presumptive MCM helicase, modulates its own expression in conjunction with Mcm1. J Biol Chem 278:25408-16
Christensen, Tim W; Tye, Bik K (2003) Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation. Mol Biol Cell 14:2206-15
Chang, Victoria K; Fitch, Michael J; Donato, Justin J et al. (2003) Mcm1 binds replication origins. J Biol Chem 278:6093-100
Lei, Ming; Cheng, Irene H; Roberts, Louis A et al. (2002) Two mcm3 mutations affect different steps in the initiation of DNA replication. J Biol Chem 277:30824-31
Yu, Xiong; VanLoock, Margaret S; Poplawski, Andrzej et al. (2002) The Methanobacterium thermoautotrophicum MCM protein can form heptameric rings. EMBO Rep 3:792-7

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