Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM034297-10A1
Application #
2177370
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1985-01-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas-Dallas
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
Richardson
State
TX
Country
United States
Zip Code
75080
Chen, Alice; AbuJarour, Ramzey J; Draper, Rockford K (2003) Evidence that the transport of ricin to the cytoplasm is independent of both Rab6A and COPI. J Cell Sci 116:3503-10
Chen, Alice; Hu, Tonghuan; Mikoryak, Carole et al. (2002) Retrograde transport of protein toxins under conditions of COPI dysfunction. Biochim Biophys Acta 1589:124-39
Draper, R K; Hudson, R T; Hu, T (2001) Use of aminoglycoside antibiotics and related compounds to study ADP-ribosylation factor (ARF)/coatomer function in Golgi traffic. Methods Enzymol 329:372-9
Hu, T; Kao, C Y; Hudson, R T et al. (1999) Inhibition of secretion by 1,3-Cyclohexanebis(methylamine), a dibasic compound that interferes with coatomer function. Mol Biol Cell 10:921-33
Hudson, R T; Draper, R K (1997) Interaction of coatomer with aminoglycoside antibiotics: evidence that coatomer has at least two dilysine binding sites. Mol Biol Cell 8:1901-10
Corboy, M J; Draper, R K (1997) Elevation of vacuolar pH inhibits the cytotoxic activity of furin-cleaved exotoxin A. Infect Immun 65:2240-2
Kao, C Y; Draper, R K (1992) Retention of secretory proteins in an intermediate compartment and disappearance of the Golgi complex in an END4 mutant of Chinese hamster ovary cells. J Cell Biol 117:701-15
Wang, R H; Colbaugh, P A; Kuo, P et al. (1992) Novel method for isolating mammalian cells defective in fluid-phase endocytosis. Somat Cell Mol Genet 18:543-51
Park, J E; Draper, R K; Brown, W J (1991) Biosynthesis of lysosomal enzymes in cells of the End3 complementation group conditionally defective in endosomal acidification. Somat Cell Mol Genet 17:137-50
Draper, R K; Goda, Y; Brodsky, F M et al. (1990) Antibodies to clathrin inhibit endocytosis but not recycling to the trans Golgi network in vitro. Science 248:1539-41

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