Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM034719-12
Application #
2177553
Study Section
Genetics Study Section (GEN)
Project Start
1985-04-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Genetics
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Dosil, M; Schandel, K A; Gupta, E et al. (2000) The C terminus of the Saccharomyces cerevisiae alpha-factor receptor contributes to the formation of preactivation complexes with its cognate G protein. Mol Cell Biol 20:5321-9
Yesilaltay, A; Jenness, D D (2000) Homo-oligomeric complexes of the yeast alpha-factor pheromone receptor are functional units of endocytosis. Mol Biol Cell 11:2873-84
Hirschman, J E; Jenness, D D (1999) Dual lipid modification of the yeast ggamma subunit Ste18p determines membrane localization of Gbetagamma. Mol Cell Biol 19:7705-11
Li, Y; Kane, T; Tipper, C et al. (1999) Yeast mutants affecting possible quality control of plasma membrane proteins. Mol Cell Biol 19:3588-99
Hirschman, J E; De Zutter, G S; Simonds, W F et al. (1997) The G beta gamma complex of the yeast pheromone response pathway. Subcellular fractionation and protein-protein interactions. J Biol Chem 272:240-8
Bukusoglu, G; Jenness, D D (1996) Agonist-specific conformational changes in the yeast alpha-factor pheromone receptor. Mol Cell Biol 16:4818-23
Song, J; Hirschman, J; Gunn, K et al. (1996) Regulation of membrane and subunit interactions by N-myristoylation of a G protein alpha subunit in yeast. J Biol Chem 271:20273-83
Schandel, K A; Jenness, D D (1994) Direct evidence for ligand-induced internalization of the yeast alpha-factor pheromone receptor. Mol Cell Biol 14:7245-55
Hasson, M S; Blinder, D; Thorner, J et al. (1994) Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway. Mol Cell Biol 14:1054-65
Konopka, J B; Jenness, D D (1991) Genetic fine-structural analysis of the Saccharomyces cerevisiae alpha-pheromone receptor. Cell Regul 2:439-52

Showing the most recent 10 out of 15 publications