Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM035695-10A1
Application #
2178017
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1985-12-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Colorado Denver
Department
Biochemistry
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Downey, Christopher D; McHenry, Charles S (2010) Chaperoning of a replicative polymerase onto a newly assembled DNA-bound sliding clamp by the clamp loader. Mol Cell 37:481-91
Yuan, Quan; McHenry, Charles S (2009) Strand displacement by DNA polymerase III occurs through a tau-psi-chi link to single-stranded DNA-binding protein coating the lagging strand template. J Biol Chem 284:31672-9
Jarvis, Thale C; Beaudry, Amber A; Bullard, James M et al. (2005) Discovery and characterization of the cryptic psi subunit of the pseudomonad DNA replicase. J Biol Chem 280:40465-73
Bullard, James M; Pritchard, Arthur E; Song, Min-Sun et al. (2002) A three-domain structure for the delta subunit of the DNA polymerase III holoenzyme delta domain III binds delta' and assembles into the DnaX complex. J Biol Chem 277:13246-56
Glover, B P; McHenry, C S (2001) The DNA polymerase III holoenzyme: an asymmetric dimeric replicative complex with leading and lagging strand polymerases. Cell 105:925-34
Song, M S; Pham, P T; Olson, M et al. (2001) The delta and delta ' subunits of the DNA polymerase III holoenzyme are essential for initiation complex formation and processive elongation. J Biol Chem 276:35165-75
Song, M S; McHenry, C S (2001) Carboxyl-terminal domain III of the delta' subunit of DNA polymerase III holoenzyme binds DnaX and supports cooperative DnaX complex assembly. J Biol Chem 276:48709-15
Glover, B P; Pritchard, A E; McHenry, C S (2001) tau binds and organizes Escherichia coli replication proteins through distinct domains: domain III, shared by gamma and tau, oligomerizes DnaX. J Biol Chem 276:35842-6
Song, M S; Dallmann, H G; McHenry, C S (2001) Carboxyl-terminal domain III of the delta' subunit of the DNA polymerase III holoenzyme binds delta. J Biol Chem 276:40668-79
Gao, D; McHenry, C S (2001) Tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain III, shared by gamma and tau, binds delta delta ' and chi psi. J Biol Chem 276:4447-53

Showing the most recent 10 out of 25 publications