Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM035791-11
Application #
2178080
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1986-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Princeton University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
002484665
City
Princeton
State
NJ
Country
United States
Zip Code
08544
Ruiz, N; Peterson, C N; Silhavy, T J (2001) RpoS-dependent transcriptional control of sprE: regulatory feedback loop. J Bacteriol 183:5974-81
Gibson, K E; Silhavy, T J (2000) SprE levels are growth phase regulated in a sigma(S)-dependent manner at the level of translation. J Bacteriol 182:4117-20
Gibson, K E; Silhavy, T J (1999) The LysR homolog LrhA promotes RpoS degradation by modulating activity of the response regulator sprE. J Bacteriol 181:563-71
Hsing, W; Russo, F D; Bernd, K K et al. (1998) Mutations that alter the kinase and phosphatase activities of the two-component sensor EnvZ. J Bacteriol 180:4538-46
Kenney, L J (1997) Kinase activity of EnvZ, an osmoregulatory signal transducing protein of Escherichia coli. Arch Biochem Biophys 346:303-11
Hsing, W; Silhavy, T J (1997) Function of conserved histidine-243 in phosphatase activity of EnvZ, the sensor for porin osmoregulation in Escherichia coli. J Bacteriol 179:3729-35
Pratt, L A; Silhavy, T J (1996) The response regulator SprE controls the stability of RpoS. Proc Natl Acad Sci U S A 93:2488-92
Pratt, L A; Hsing, W; Gibson, K E et al. (1996) From acids to osmZ: multiple factors influence synthesis of the OmpF and OmpC porins in Escherichia coli. Mol Microbiol 20:911-7
Patterson, G I; Chandler, V L (1995) Paramutation in maize and related allelic interactions. Curr Top Microbiol Immunol 197:121-41
Kenney, L J; Bauer, M D; Silhavy, T J (1995) Phosphorylation-dependent conformational changes in OmpR, an osmoregulatory DNA-binding protein of Escherichia coli. Proc Natl Acad Sci U S A 92:8866-70

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