Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM036238-17S1
Application #
6824682
Study Section
Metallobiochemistry Study Section (BMT)
Program Officer
Preusch, Peter C
Project Start
1986-12-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
17
Fiscal Year
2004
Total Cost
$41,751
Indirect Cost
Name
North Carolina State University Raleigh
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
042092122
City
Raleigh
State
NC
Country
United States
Zip Code
27695
Lindsey, Jonathan S (2015) De novo synthesis of gem-dialkyl chlorophyll analogues for probing and emulating our green world. Chem Rev 115:6534-620
Huang, Liyi; Huang, Ying-Ying; Mroz, Pawel et al. (2010) Stable synthetic cationic bacteriochlorins as selective antimicrobial photosensitizers. Antimicrob Agents Chemother 54:3834-41
Mroz, Pawel; Huang, Ying-Ying; Szokalska, Angelika et al. (2010) Stable synthetic bacteriochlorins overcome the resistance of melanoma to photodynamic therapy. FASEB J 24:3160-70
Huang, Ying-Ying; Mroz, Pawel; Zhiyentayev, Timur et al. (2010) In vitro photodynamic therapy and quantitative structure-activity relationship studies with stable synthetic near-infrared-absorbing bacteriochlorin photosensitizers. J Med Chem 53:4018-27
Mroz, Pawel; Bhaumik, Jayeeta; Dogutan, Dilek K et al. (2009) Imidazole metalloporphyrins as photosensitizers for photodynamic therapy: role of molecular charge, central metal and hydroxyl radical production. Cancer Lett 282:63-76
Kee, Hooi Ling; Bhaumik, Jayeeta; Diers, James R et al. (2008) Photophysical Characterization of Imidazolium-Substituted Pd(II), In(III), and Zn(II) Porphyrins as Photosensitizers for Photodynamic Therapy. J Photochem Photobiol A Chem 200:346-355
Borbas, K Eszter; Ruzie, Christian; Lindsey, Jonathan S (2008) Swallowtail bacteriochlorins. Lipophilic absorbers for the near-infrared. Org Lett 10:1931-4
Muresan, Ana Z; Lindsey, Jonathan S (2008) Design and synthesis of water-soluble bioconjugatable trans-AB-porphyrins. Tetrahedron 64:11440-11448
Dogutan, Dilek Kiper; Lindsey, Jonathan S (2008) Investigation of the scope of a new route to ABCD-bilanes and ABCD-porphyrins. J Org Chem 73:6728-42
Borbas, K Eszter; Kee, Hooi Ling; Holten, Dewey et al. (2008) A compact water-soluble porphyrin bearing an iodoacetamido bioconjugatable site. Org Biomol Chem 6:187-94

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