Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
7R01GM036510-09
Application #
3290613
Study Section
Molecular Biology Study Section (MBY)
Project Start
1986-07-01
Project End
1994-07-31
Budget Start
1993-12-21
Budget End
1994-07-31
Support Year
9
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Adams Martin, A; Dionne, I; Wellinger, R J et al. (2000) The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasis. Mol Cell Biol 20:786-96
Lavoie, B D; Tuffo, K M; Oh, S et al. (2000) Mitotic chromosome condensation requires Brn1p, the yeast homologue of Barren. Mol Biol Cell 11:1293-304
Merrill, B J; Holm, C (1999) A requirement for recombinational repair in Saccharomyces cerevisiae is caused by DNA replication defects of mec1 mutants. Genetics 153:595-605
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Chen, C; Merrill, B J; Lau, P J et al. (1999) Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repair. Mol Cell Biol 19:7801-15
Merrill, B J; Holm, C (1998) The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis. Genetics 148:611-24
Adams, A K; Holm, C (1996) Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae. Mol Cell Biol 16:4614-20
Johnson, R E; Kovvali, G K; Guzder, S N et al. (1996) Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair. J Biol Chem 271:27987-90
McAlear, M A; Tuffo, K M; Holm, C (1996) The large subunit of replication factor C (Rfc1p/Cdc44p) is required for DNA replication and DNA repair in Saccharomyces cerevisiae. Genetics 142:65-78
Amin, N S; Holm, C (1996) In vivo analysis reveals that the interdomain region of the yeast proliferating cell nuclear antigen is important for DNA replication and DNA repair. Genetics 144:479-93

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