Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM036652-11
Application #
2178475
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1986-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cornell University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Pelaseyed, Thaher; Viswanatha, Raghuvir; Sauvanet, Cécile et al. (2017) Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism. Elife 6:
Sauvanet, Cécile; Wayt, Jessica; Pelaseyed, Thaher et al. (2015) Structure, regulation, and functional diversity of microvilli on the apical domain of epithelial cells. Annu Rev Cell Dev Biol 31:593-621
Sauvanet, Cécile; Garbett, Damien; Bretscher, Anthony (2015) The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation. Mol Biol Cell 26:3615-27
Widemann, Brigitte C; Acosta, Maria T; Ammoun, Sylvia et al. (2014) CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. Am J Med Genet A 164A:563-78
Wayt, Jessica; Bretscher, Anthony (2014) Cordon Bleu serves as a platform at the basal region of microvilli, where it regulates microvillar length through its WH2 domains. Mol Biol Cell 25:2817-27
Garbett, Damien; Bretscher, Anthony (2014) The surprising dynamics of scaffolding proteins. Mol Biol Cell 25:2315-9
Viswanatha, Raghuvir; Bretscher, Anthony; Garbett, Damien (2014) Dynamics of ezrin and EBP50 in regulating microvilli on the apical aspect of epithelial cells. Biochem Soc Trans 42:189-94
Garbett, Damien; Sauvanet, Cécile; Viswanatha, Raghuvir et al. (2013) The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics. Mol Biol Cell 24:3381-92
Viswanatha, Raghuvir; Wayt, Jessica; Ohouo, Patrice Y et al. (2013) Interactome analysis reveals ezrin can adopt multiple conformational states. J Biol Chem 288:35437-51
Bretscher, Anthony (2013) Magazine or journal--what is the difference? The role of the monitoring editor. Mol Biol Cell 24:887-9

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