Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM037009-10
Application #
2178635
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1986-07-01
Project End
1999-11-30
Budget Start
1995-12-11
Budget End
1996-11-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Utah
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Gonciarz-Swiatek, Malgorzata; Rechsteiner, Martin (2006) Proteasomes and antigen presentation: evidence that a KEKE motif does not promote presentation of the class I epitope SIINFEKL. Mol Immunol 43:1993-2001
Mahaffey, David T; Gorbea, Carlos; Rechsteiner, Martin (2003) Evidence that DNA replication is not regulated by ubiquitin-dependent proteolysis in Xenopus egg extract. Exp Cell Res 288:225-34
Matilla, A; Gorbea, C; Einum, D D et al. (2001) Association of ataxin-7 with the proteasome subunit S4 of the 19S regulatory complex. Hum Mol Genet 10:2821-31
Thrower, J S; Hoffman, L; Rechsteiner, M et al. (2000) Recognition of the polyubiquitin proteolytic signal. EMBO J 19:94-102
Turnell, A S; Grand, R J; Gorbea, C et al. (2000) Regulation of the 26S proteasome by adenovirus E1A. EMBO J 19:4759-73
Gorbea, C; Taillandier, D; Rechsteiner, M (2000) Mapping subunit contacts in the regulatory complex of the 26 S proteasome. S2 and S5b form a tetramer with ATPase subunits S4 and S7. J Biol Chem 275:875-82
Mahaffey, D; Rechsteiner, M (1999) Discrimination between ubiquitin-dependent and ubiquitin-independent proteolytic pathways by the 26S proteasome subunit 5a. FEBS Lett 450:123-5
Gorbea, C; Taillandier, D; Rechsteiner, M (1999) Assembly of the regulatory complex of the 26S proteasome. Mol Biol Rep 26:15-9
Hoffman, L; Gorbea, C; Rechsteiner, M (1999) Identification, molecular cloning, and characterization of subunit 11 of the human 26S proteasome. FEBS Lett 449:88-92
Zhang, Z; Krutchinsky, A; Endicott, S et al. (1999) Proteasome activator 11S REG or PA28: recombinant REG alpha/REG beta hetero-oligomers are heptamers. Biochemistry 38:5651-8

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