Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM037699-09
Application #
2178906
Study Section
Immunobiology Study Section (IMB)
Project Start
1987-04-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Borggrefe, T; Keshavarzi, S; Gross, B et al. (2001) Impaired IgE response in SWAP-70-deficient mice. Eur J Immunol 31:2467-75
Masat, L; Liddell, R A; Mock, B A et al. (2000) Mapping of the SWAP70 gene to mouse chromosome 7 and human chromosome 11p15. Immunogenetics 51:16-9
Masat, L; Caldwell, J; Armstrong, R et al. (2000) Association of SWAP-70 with the B cell antigen receptor complex. Proc Natl Acad Sci U S A 97:2180-4
Borggrefe, T; Masat, L; Wabl, M et al. (1999) Cellular, intracellular, and developmental expression patterns of murine SWAP-70. Eur J Immunol 29:1812-22
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Borggrefe, T; Wabl, M; Akhmedov, A T et al. (1998) A B-cell-specific DNA recombination complex. J Biol Chem 273:17025-35
Cascalho, M; Wong, J; Steinberg, C et al. (1998) Mismatch repair co-opted by hypermutation. Science 279:1207-10
Bachl, J; Olsson, C; Chitkara, N et al. (1998) The Ig mutator is dependent on the presence, position, and orientation of the large intron enhancer. Proc Natl Acad Sci U S A 95:2396-9
Bachl, J; Steinberg, C; Wabl, M (1997) Critical test of hot spot motifs for immunoglobulin hypermutation. Eur J Immunol 27:3398-403
Cascalho, M; Wong, J; Wabl, M (1997) VH gene replacement in hyperselected B cells of the quasimonoclonal mouse. J Immunol 159:5795-801

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