Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM037705-09
Application #
2178918
Study Section
Experimental Virology Study Section (EVR)
Project Start
1986-12-01
Project End
1997-03-31
Budget Start
1995-09-01
Budget End
1997-03-31
Support Year
9
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Princeton University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
002484665
City
Princeton
State
NJ
Country
United States
Zip Code
08544
Pérez-Berná, Ana J; Mangel, Walter F; McGrath, William J et al. (2014) Processing of the l1 52/55k protein by the adenovirus protease: a new substrate and new insights into virion maturation. J Virol 88:1513-24
Ortega-Esteban, A; Pérez-Berná, A J; Menéndez-Conejero, R et al. (2013) Monitoring dynamics of human adenovirus disassembly induced by mechanical fatigue. Sci Rep 3:1434
Graziano, Vito; Luo, Guobin; Blainey, Paul C et al. (2013) Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: II. adenovirus proteinase is activated in an unusual one-dimensional biochemical reaction. J Biol Chem 288:2068-80
Blainey, Paul C; Graziano, Vito; Pérez-Berná, Ana J et al. (2013) Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: IV. viral proteinase slides along DNA to locate and process its substrates. J Biol Chem 288:2092-102
Pérez-Berná, Ana J; Ortega-Esteban, Alvaro; Menéndez-Conejero, Rosa et al. (2012) The role of capsid maturation on adenovirus priming for sequential uncoating. J Biol Chem 287:31582-95
Pérez-Berná, Ana J; Marabini, Roberto; Scheres, Sjors H W et al. (2009) Structure and uncoating of immature adenovirus. J Mol Biol 392:547-57
LeRoy, Gary; Rickards, Brenden; Flint, S J (2008) The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription. Mol Cell 30:51-60
Huang, Wenlin; Flint, S J (2003) Unusual properties of adenovirus E2E transcription by RNA polymerase III. J Virol 77:4015-24
Postel, E H; Ferrone, C A (1994) Nucleoside diphosphate kinase enzyme activity of NM23-H2/PuF is not required for its DNA binding and in vitro transcriptional functions. J Biol Chem 269:8627-30
Chen, H; Flint, S J (1992) Mutational analysis of the adenovirus 2 IVa2 initiator and downstream elements. J Biol Chem 267:25457-65

Showing the most recent 10 out of 13 publications