Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM037706-16
Application #
6476473
Study Section
Special Emphasis Panel (ZRG2-BIOL-1 (01))
Program Officer
Greenberg, Judith H
Project Start
1986-12-01
Project End
2002-11-30
Budget Start
2001-12-01
Budget End
2002-11-30
Support Year
16
Fiscal Year
2002
Total Cost
$400,338
Indirect Cost
Name
Carnegie Institution of Washington, D.C.
Department
Type
DUNS #
072641707
City
Washington
State
DC
Country
United States
Zip Code
20005
Arribere, Joshua A; Fire, Andrew Z (2018) Nonsense mRNA suppression via nonstop decay. Elife 7:
Silas, Sukrit; Jain, Nimit; Stadler, Michael et al. (2018) A Small RNA Isolation and Sequencing Protocol and Its Application to Assay CRISPR RNA Biogenesis in Bacteria. Bio Protoc 8:
Mohr, Georg; Silas, Sukrit; Stamos, Jennifer L et al. (2018) A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition. Mol Cell 72:700-714.e8
Silas, Sukrit; Lucas-Elio, Patricia; Jackson, Simon A et al. (2017) Type III CRISPR-Cas systems can provide redundancy to counteract viral escape from type I systems. Elife 6:
Fu, Becky Xu Hua; Wainberg, Michael; Kundaje, Anshul et al. (2017) High-Throughput Characterization of Cascade type I-E CRISPR Guide Efficacy Reveals Unexpected PAM Diversity and Target Sequence Preferences. Genetics 206:1727-1738
Silas, Sukrit; Makarova, Kira S; Shmakov, Sergey et al. (2017) On the Origin of Reverse Transcriptase-Using CRISPR-Cas Systems and Their Hyperdiverse, Enigmatic Spacer Repertoires. MBio 8:
Shoura, Massa J; Gabdank, Idan; Hansen, Loren et al. (2017) Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens. G3 (Bethesda) 7:3295-3303
Frøkjær-Jensen, Christian; Jain, Nimit; Hansen, Loren et al. (2016) An Abundant Class of Non-coding DNA Can Prevent Stochastic Gene Silencing in the C. elegans Germline. Cell 166:343-357
Fu, Becky X H; St Onge, Robert P; Fire, Andrew Z et al. (2016) Distinct patterns of Cas9 mismatch tolerance in vitro and in vivo. Nucleic Acids Res 44:5365-77
Arribere, Joshua A; Cenik, Elif S; Jain, Nimit et al. (2016) Translation readthrough mitigation. Nature 534:719-23

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