Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM038219-09
Application #
2179212
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1987-04-01
Project End
1996-09-30
Budget Start
1995-04-01
Budget End
1996-09-30
Support Year
9
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Biochemistry
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Chatterjee, Nimrat; Lin, Yunfu; Wilson, John H (2016) Mismatch repair enhances convergent transcription-induced cell death at trinucleotide repeats by activating ATR. DNA Repair (Amst) 42:26-32
Chatterjee, Nimrat; Lin, Yunfu; Yotnda, Patricia et al. (2016) Environmental Stress Induces Trinucleotide Repeat Mutagenesis in Human Cells by Alt-Nonhomologous End Joining Repair. J Mol Biol 428:2978-80
Chatterjee, Nimrat; Lin, Yunfu; Wilson, John H (2016) Fanconi anemia pathway regulates convergent transcription-induced cell death at trinucleotide repeats in human cells. Postdoc J 4:46-54
Lin, William Y; Wilson, John H; Lin, Yunfu (2013) Repair of chromosomal double-strand breaks by precise ligation in human cells. DNA Repair (Amst) 12:480-7
Mittelman, David; Wilson, John H (2013) The fractured genome of HeLa cells. Genome Biol 14:111
Lin, Yunfu; Leng, Mei; Wan, Ma et al. (2010) Convergent transcription through a long CAG tract destabilizes repeats and induces apoptosis. Mol Cell Biol 30:4435-51
Lin, Yunfu; Wilson, John H (2009) Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells. DNA Repair (Amst) 8:878-85
Dion, Vincent; Lin, Yunfu; Price, Brandee A et al. (2008) Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination. DNA Repair (Amst) 7:313-20