Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM038436-18S1
Application #
6940562
Study Section
Medicinal Chemistry Study Section (MCHA)
Program Officer
Schwab, John M
Project Start
1988-02-01
Project End
2008-01-31
Budget Start
2004-02-01
Budget End
2005-01-31
Support Year
18
Fiscal Year
2004
Total Cost
$22,992
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Doherty, Joanne R; Yang, Chunying; Scott, Kristen E N et al. (2014) Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis. Cancer Res 74:908-20
Chen, Ming; Roush, William R (2013) Enantiodivergent Hydroboration Reactions of a Racemic Allenylsilane with Diisopinocampheylborane and Curtin-Hammett Controlled Double Asymmetric Crotylboration Reactions of (S)-E-?-phenyldimethylsilyl( d diisopinocamp Tetrahedron 69:5468-5475
Nuhant, Philippe; Allais, Christophe; Roush, William R (2013) Diisopinocampheylborane-mediated reductive aldol reactions: highly enantio- and diastereoselective synthesis of syn aldols from N-acryloylmorpholine. Angew Chem Int Ed Engl 52:8703-7
Nuhant, Philippe; Roush, William R (2013) Enantio- and diastereoselective synthesis of N-acetyl dihydrotetrafibricin methyl ester. J Am Chem Soc 135:5340-3
Allais, Christophe; Nuhant, Philippe; Roush, William R (2013) (Diisopinocampheyl)borane-mediated reductive aldol reactions of acrylate esters: enantioselective synthesis of anti-aldols. Org Lett 15:3922-5
Chen, Ming; Roush, William R (2013) Crotylboron-based synthesis of the polypropionate units of chaxamycins A/D, salinisporamycin, and rifamycin S. J Org Chem 78:3-8
Kister, Jeremy; Ess, Daniel H; Roush, William R (2013) Enantio- and diastereoselective synthesis of syn-*-hydroxy-*-vinyl carboxylic esters via reductive aldol reactions of ethyl allenecarboxylate with 10-TMS-9-Borabicyclo[3.3.2]decane and DFT analysis of the hydroboration pathway. Org Lett 15:5436-9
Abbott, Jason R; Roush, William R (2013) Stereoselective synthesis of the disaccharide unit of incednine. Org Lett 15:62-4
Chen, Ming; Roush, William R (2013) Enantioselective synthesis of (Z)- and (E)-2-methyl-1,5-anti-pentenediols via an allene hydroboration-double-allylboration reaction sequence. J Am Chem Soc 135:9512-7
Tsai, Andy S; Chen, Ming; Roush, William R (2013) Chiral Brønsted Acid Catalyzed Enantioselective Synthesis of anti-Homopropargyl Alcohols via Kinetic Resolution-Aldehyde Allenylboration Using Racemic Allenylboronates. Org Lett 15:2325

Showing the most recent 10 out of 53 publications