Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM038838-10
Application #
2179572
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1987-07-01
Project End
1998-03-31
Budget Start
1996-07-01
Budget End
1998-03-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Nekouzadeh, Ali; Pryse, Kenneth M; Elson, Elliot L et al. (2008) Stretch-activated force shedding, force recovery, and cytoskeletal remodeling in contractile fibroblasts. J Biomech 41:2964-71
Nekouzadeh, Ali; Pryse, Kenneth M; Elson, Elliot L et al. (2007) A simplified approach to quasi-linear viscoelastic modeling. J Biomech 40:3070-8
Pablo Marquez, J; Genin, Guy M; Elson, Elliot L (2006) On the application of strain factors for approximation of the contribution of anisotropic cells to the mechanics of a tissue construct. J Biomech 39:2145-51
Marquez, J Pablo; Genin, Guy M; Pryse, Kenneth M et al. (2006) Cellular and matrix contributions to tissue construct stiffness increase with cellular concentration. Ann Biomed Eng 34:1475-82
Chattopadhyay, Krishnananda; Elson, Elliot L; Frieden, Carl (2005) The kinetics of conformational fluctuations in an unfolded protein measured by fluorescence methods. Proc Natl Acad Sci U S A 102:2385-9
Chattopadhyay, Krishnananda; Saffarian, Saveez; Elson, Elliot L et al. (2005) Measuring unfolding of proteins in the presence of denaturant using fluorescence correlation spectroscopy. Biophys J 88:1413-22
Marquez, J Pablo; Genin, Guy M; Zahalak, George I et al. (2005) Thin bio-artificial tissues in plane stress: the relationship between cell and tissue strain, and an improved constitutive model. Biophys J 88:765-77
Emmert, Daniel A; Fee, Judy A; Goeckeler, Zoe M et al. (2004) Rho-kinase-mediated Ca2+-independent contraction in rat embryo fibroblasts. Am J Physiol Cell Physiol 286:C8-21
Saffarian, Saveez; Collier, Ivan E; Marmer, Barry L et al. (2004) Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen. Science 306:108-11
Wakatsuki, T; Fee, J A; Elson, E L (2004) Phenotypic screening for pharmaceuticals using tissue constructs. Curr Pharm Biotechnol 5:181-9

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