Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
7R01GM039014-05
Application #
3295769
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1991-01-01
Project End
1995-06-30
Budget Start
1991-01-01
Budget End
1991-06-30
Support Year
5
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Arizona
Department
Type
Schools of Earth Sciences/Natur
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Giraudo, Maeva; Unnithan, G Chandran; Le Goff, Gaƫlle et al. (2010) Regulation of cytochrome P450 expression in Drosophila: Genomic insights. Pestic Biochem Physiol 97:115-122
Murataliev, Marat B; Guzov, Victor M; Walker, F Ann et al. (2008) P450 reductase and cytochrome b5 interactions with cytochrome P450: effects on house fly CYP6A1 catalysis. Insect Biochem Mol Biol 38:1008-15
Jacobsen, Neil E; Kover, Katalin E; Murataliev, Marat B et al. (2006) Structure and stereochemistry of products of hydroxylation of human steroid hormones by a housefly cytochrome P450 (CYP6A1). Magn Reson Chem 44:467-74
Helvig, Christian; Tijet, Nathalie; Feyereisen, Rene et al. (2004) Drosophila melanogaster CYP6A8, an insect P450 that catalyzes lauric acid (omega-1)-hydroxylation. Biochem Biophys Res Commun 325:1495-502
Murataliev, Marat B; Trinh, Long N; Moser, Lani V et al. (2004) Chimeragenesis of the fatty acid binding site of cytochrome P450BM3. Replacement of residues 73-84 with the homologous residues from the insect cytochrome P450 CYP4C7. Biochemistry 43:1771-80
Murataliev, Marat B; Feyereisen, Rene; Walker, F Ann (2004) Electron transfer by diflavin reductases. Biochim Biophys Acta 1698:1-26
Tijet, N; Helvig, C; Feyereisen, R (2001) The cytochrome P450 gene superfamily in Drosophila melanogaster: annotation, intron-exon organization and phylogeny. Gene 262:189-98
Sabourault, C; Guzov, V M; Koener, J F et al. (2001) Overproduction of a P450 that metabolizes diazinon is linked to a loss-of-function in the chromosome 2 ali-esterase (MdalphaE7) gene in resistant house flies. Insect Mol Biol 10:609-18
Murataliev, M B; Feyereisen, R (2000) Functional interactions in cytochrome P450BM3. Evidence that NADP(H) binding controls redox potentials of the flavin cofactors. Biochemistry 39:12699-707
Murataliev, M B; Feyereisen, R (2000) Interaction of NADP(H) with oxidized and reduced P450 reductase during catalysis. Studies with nucleotide analogues. Biochemistry 39:5066-74

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