Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM039458-04
Application #
3296464
Study Section
Molecular Biology Study Section (MBY)
Project Start
1988-02-01
Project End
1991-06-30
Budget Start
1991-02-01
Budget End
1991-06-30
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Whitehead Institute for Biomedical Research
Department
Type
DUNS #
076580745
City
Cambridge
State
MA
Country
United States
Zip Code
02142
Ramakrishnan, Parameswaran; Yui, Mary A; Tomalka, Jeffrey A et al. (2016) Deficiency of Nuclear Factor-?B c-Rel Accelerates the Development of Autoimmune Diabetes in NOD Mice. Diabetes 65:2367-79
Ramakrishnan, Parameswaran; Clark, Peter M; Mason, Daniel E et al. (2013) Activation of the transcriptional function of the NF-?B protein c-Rel by O-GlcNAc glycosylation. Sci Signal 6:ra75
Hao, Shengli; Baltimore, David (2013) RNA splicing regulates the temporal order of TNF-induced gene expression. Proc Natl Acad Sci U S A 110:11934-9
Ea, Chee-Kwee; Hao, ShengLi; Yeo, Kok Siong et al. (2012) EHMT1 protein binds to nuclear factor-?B p50 and represses gene expression. J Biol Chem 287:31207-17
Ramakrishnan, P; Kahn, D A; Baltimore, D (2011) Anti-apoptotic effect of hyperglycemia can allow survival of potentially autoreactive T cells. Cell Death Differ 18:690-9
Ramakrishnan, Parameswaran; Baltimore, David (2011) Sam68 is required for both NF-*B activation and apoptosis signaling by the TNF receptor. Mol Cell 43:167-79
Ea, Chee-Kwee; Baltimore, David (2009) Regulation of NF-kappaB activity through lysine monomethylation of p65. Proc Natl Acad Sci U S A 106:18972-7
Lee, Timothy K; Denny, Elissa M; Sanghvi, Jayodita C et al. (2009) A noisy paracrine signal determines the cellular NF-kappaB response to lipopolysaccharide. Sci Signal 2:ra65
Hao, Shengli; Baltimore, David (2009) The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules. Nat Immunol 10:281-8
Taganov, Konstantin D; Boldin, Mark P; Chang, Kuang-Jung et al. (2006) NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A 103:12481-6

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