Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM040313-07
Application #
2180253
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1988-09-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Microbiology/Immun/Virology
Type
Schools of Earth Sciences/Natur
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Mattes, Theodoric A; Escalante-Semerena, Jorge C (2018) Facile isolation of ?-ribazole from vitamin B12 hydrolysates using boronate affinity chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 1090:52-55
Park, Kiyoung; Mera, Paola E; Moore, Theodore C et al. (2015) Unprecedented Mechanism Employed by the Salmonella enterica EutT ATP:Co(I)rrinoid Adenosyltransferase Precludes Adenosylation of Incomplete Co(II)rrinoids. Angew Chem Int Ed Engl 54:7158-61
Newmister, Sean A; Otte, Michele M; Escalante-Semerena, Jorge C et al. (2011) Structure and mutational analysis of the archaeal GTP:AdoCbi-P guanylyltransferase (CobY) from Methanocaldococcus jannaschii: insights into GTP binding and dimerization. Biochemistry 50:5301-13
Mera, Paola E; Escalante-Semerena, Jorge C (2010) Dihydroflavin-driven adenosylation of 4-coordinate Co(II) corrinoids: are cobalamin reductases enzymes or electron transfer proteins? J Biol Chem 285:2911-7
Gray, Michael J; Escalante-Semerena, Jorge C (2010) A new pathway for the synthesis of ?-ribazole-phosphate in Listeria innocua. Mol Microbiol 77:1429-38
Claas, Kathy R; Parrish, J R; Maggio-Hall, L A et al. (2010) Functional analysis of the nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) enzyme, involved in the late steps of coenzyme B12 biosynthesis in Salmonella enterica. J Bacteriol 192:145-54
Otte, Michele M; Escalante-Semerena, Jorge C (2009) Biochemical characterization of the GTP:adenosylcobinamide-phosphate guanylyltransferase (CobY) enzyme of the hyperthermophilic archaeon Methanocaldococcus jannaschii. Biochemistry 48:5882-9
Gray, Michael J; Escalante-Semerena, Jorge C (2009) The cobinamide amidohydrolase (cobyric acid-forming) CbiZ enzyme: a critical activity of the cobamide remodelling system of Rhodobacter sphaeroides. Mol Microbiol 74:1198-210
Gray, Michael J; Escalante-Semerena, Jorge C (2009) In vivo analysis of cobinamide salvaging in Rhodobacter sphaeroides strain 2.4.1. J Bacteriol 191:3842-51
Mera, Paola E; St Maurice, Martin; Rayment, Ivan et al. (2009) Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. Biochemistry 48:3138-45

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