Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM040457-07
Application #
2180342
Study Section
Physiology Study Section (PHY)
Project Start
1988-07-01
Project End
1996-12-31
Budget Start
1994-07-01
Budget End
1996-12-31
Support Year
7
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Rochester
Department
Physiology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Thompson, Jill L; Zhao, Yue; Stathopulos, Peter B et al. (2018) Phosphorylation-mediated structural changes within the SOAR domain of stromal interaction molecule 1 enable specific activation of distinct Orai channels. J Biol Chem 293:3145-3155
Shuttleworth, Trevor J (2017) Selective activation of distinct Orai channels by STIM1. Cell Calcium 63:40-42
Thompson, Jill L; Shuttleworth, Trevor J (2015) Anchoring protein AKAP79-mediated PKA phosphorylation of STIM1 determines selective activation of the ARC channel, a store-independent Orai channel. J Physiol 593:559-72
Duquette, Mark; Nadler, Monica; Okuhara, Dayne et al. (2014) Members of the thrombospondin gene family bind stromal interaction molecule 1 and regulate calcium channel activity. Matrix Biol 37:15-24
Thompson, Jill L; Shuttleworth, Trevor J (2013) How many Orai's does it take to make a CRAC channel? Sci Rep 3:1961
Thompson, Jill L; Shuttleworth, Trevor J (2013) Molecular basis of activation of the arachidonate-regulated Ca2+ (ARC) channel, a store-independent Orai channel, by plasma membrane STIM1. J Physiol 591:3507-23
Thompson, Jill L; Shuttleworth, Trevor J (2013) Exploring the unique features of the ARC channel, a store-independent Orai channel. Channels (Austin) 7:364-73
Shuttleworth, Trevor J (2012) Orai3--the 'exceptional' Orai? J Physiol 590:241-57
Shuttleworth, Trevor J (2012) Orai channels - new insights, new ideas. J Physiol 590:4155-6
Shuttleworth, Trevor J (2012) STIM and Orai proteins and the non-capacitative ARC channels. Front Biosci (Landmark Ed) 17:847-60

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