Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM040586-09
Application #
2180459
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1988-08-01
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Florida
Department
Surgery
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Stortz, Julie A; Murphy, Tyler J; Raymond, Steven L et al. (2018) Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis. Shock 49:249-258
Horiguchi, Hiroyuki; Loftus, Tyler J; Hawkins, Russell B et al. (2018) Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy. Front Immunol 9:595
Mira, Juan C; Nacionales, Dina C; Loftus, Tyler J et al. (2018) Mouse Injury Model of Polytrauma and Shock. Methods Mol Biol 1717:1-15
Hawkins, Russell B; Raymond, Steven L; Stortz, Julie A et al. (2018) Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome. Front Immunol 9:1511
Stortz, Julie A; Mira, Juan C; Raymond, Steven L et al. (2018) Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients. J Trauma Acute Care Surg 84:342-349
Brakenridge, Scott C; Efron, Philip A; Stortz, Julie A et al. (2018) The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients. J Trauma Acute Care Surg 85:247-255
Raymond, Steven L; Holden, David C; Mira, Juan C et al. (2017) Microbial recognition and danger signals in sepsis and trauma. Biochim Biophys Acta Mol Basis Dis 1863:2564-2573
Stortz, Julie A; Efron, Philip A (2017) Editorial: Myeloid-derived suppressor cells: a new therapeutic target in sepsis patients. J Leukoc Biol 102:185-187
Mira, Juan C; Cuschieri, Joseph; Ozrazgat-Baslanti, Tezcan et al. (2017) The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers. Crit Care Med 45:1989-1996
Raymond, Steven L; López, María Cecilia; Baker, Henry V et al. (2017) Unique transcriptomic response to sepsis is observed among patients of different age groups. PLoS One 12:e0184159

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