Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM040600-09
Application #
2180468
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1988-08-01
Project End
1998-06-30
Budget Start
1996-08-01
Budget End
1998-06-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Biology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Tsui, Jennifer; Inagaki, Masaki; Schulman, Howard (2005) Calcium/calmodulin-dependent protein kinase II (CaMKII) localization acts in concert with substrate targeting to create spatial restriction for phosphorylation. J Biol Chem 280:9210-6
Schulman, Howard (2004) Activity-dependent regulation of calcium/calmodulin-dependent protein kinase II localization. J Neurosci 24:8399-403
Bradshaw, J Michael; Kubota, Yoshi; Meyer, Tobias et al. (2003) An ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling. Proc Natl Acad Sci U S A 100:10512-7
Zhang, Tong; Johnson, Eric N; Gu, Yusu et al. (2002) The cardiac-specific nuclear delta(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J Biol Chem 277:1261-7
Hudmon, Andy; Schulman, Howard (2002) Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II. Biochem J 364:593-611
Singla, S I; Hudmon, A; Goldberg, J M et al. (2001) Molecular characterization of calmodulin trapping by calcium/calmodulin-dependent protein kinase II. J Biol Chem 276:29353-60
Chen, Y A; Scales, S J; Duvvuri, V et al. (2001) Calcium regulation of exocytosis in PC12 cells. J Biol Chem 276:26680-7
Bayer, K U; Schulman, H (2001) Regulation of signal transduction by protein targeting: the case for CaMKII. Biochem Biophys Res Commun 289:917-23
Browne, S H; Kang, J; Akk, G et al. (2001) Kinetic and pharmacological properties of GABA(A) receptors in single thalamic neurons and GABA(A) subunit expression. J Neurophysiol 86:2312-22
De Koninck, P; Schulman, H (1998) Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science 279:227-30

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