Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
7R01GM040700-04
Application #
3298501
Study Section
Molecular Biology Study Section (MBY)
Project Start
1990-12-01
Project End
1993-06-30
Budget Start
1990-12-01
Budget End
1991-06-30
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Melcher, K; Xu, H E (2001) Gal80-Gal80 interaction on adjacent Gal4p binding sites is required for complete GAL gene repression. EMBO J 20:841-51
Zheng, W; Xu, H E; Johnston, S A (1997) The cysteine-peptidase bleomycin hydrolase is a member of the galactose regulon in yeast. J Biol Chem 272:30350-5
Fancy, D A; Melcher, K; Johnston, S A et al. (1996) New chemistry for the study of multiprotein complexes: the six-histidine tag as a receptor for a protein crosslinking reagent. Chem Biol 3:551-9
Kodadek, T; Johnston, S A (1995) The dangers of 'splicing and dicing': on the use of chimeric transcriptional activators in vitro. Chem Biol 2:187-94
Joshua-Tor, L; Xu, H E; Johnston, S A et al. (1995) Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science 269:945-50
Xu, H E; Kodadek, T; Johnston, S A (1995) A single GAL4 dimer can maximally activate transcription under physiological conditions. Proc Natl Acad Sci U S A 92:7677-80
Parks, T D; Leuther, K K; Howard, E D et al. (1994) Release of proteins and peptides from fusion proteins using a recombinant plant virus proteinase. Anal Biochem 216:413-7
Van Hoy, M; Leuther, K K; Kodadek, T et al. (1993) The acidic activation domains of the GCN4 and GAL4 proteins are not alpha helical but form beta sheets. Cell 72:587-94
Vashee, S; Xu, H; Johnston, S A et al. (1993) How do ""Zn2 cys6"" proteins distinguish between similar upstream activation sites? Comparison of the DNA-binding specificity of the GAL4 protein in vitro and in vivo. J Biol Chem 268:24699-706
Salmeron Jr, J M; Langdon, S D; Johnston, S A (1989) Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. Mol Cell Biol 9:2950-6