Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM041560-14
Application #
2180912
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1982-04-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Indiana University Bloomington
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
006046700
City
Bloomington
State
IN
Country
United States
Zip Code
47401
Williams, David R; Claeboe, Christopher D; Liang, Bo et al. (2012) A bidirectional S(E)' strategy for 1,5-syn and 1,5-anti stereocontrol toward the synthesis of complex polyols. Org Lett 14:3866-9
Williams, David R; Klein, J Cullen; Chow, Nicholas S C (2011) Studies of intramolecular Diels-Alder reactions of nitroalkenes for the stereocontrolled synthesis of trans-decalin ring systems. Tetrahedron Lett 52:2120-2123
Williams, David R; Walsh, Martin J; Claeboe, Christopher D et al. (2009) Studies for the synthesis of marine natural products. Pure Appl Chem 81:181
Williams, David R; Nag, Partha P; Zorn, Nicolas (2008) Strategies for the synthesis of the novel antitumor agent peloruside A. Curr Opin Drug Discov Devel 11:251-71
Williams, David R; Reeves, Jonathan T; Nag, Partha P et al. (2006) Studies of the generation and pericyclic behavior of cyclic pentadienyl carbanions. Alkylation reactions as an efficient route to functionalized cis-bicyclo[3.3.0]octenes. J Am Chem Soc 128:12339-48
Williams, David R; Morales-Ramos, Angel I; Williams, Catherine M (2006) Reactivity studies of 3,3-bis(trimethylsilyl)-2-methyl-1-propene in Lewis acid-catalyzed allylation reactions. Org Lett 8:4393-6
Williams, David R; Berliner, Martin A; Stroup, Bryan W et al. (2005) Samarium Barbier reactions of alpha-iodomethyloxazoles and thiazoles with aliphatic aldehydes. Org Lett 7:4099-102
Williams, David R; Kammler, David C; Donnell, Andrew F et al. (2005) Total synthesis of (+)-apiosporamide: assignment of relative and absolute configuration. Angew Chem Int Ed Engl 44:6715-8
Williams, David R; Reeves, Jonathan T (2004) Carbolithiation for the generation of cyclooctadienyl anions and tandem electrocyclization/alkylation to functionalized cis-bicyclo[3.3.0]octenes. J Am Chem Soc 126:3434-5
Williams, David R; Kiryanov, Andre A; Emde, Ulrich et al. (2004) Studies of stereocontrolled allylation reactions for the total synthesis of phorboxazole A. Proc Natl Acad Sci U S A 101:12058-63

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