Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM041815-03
Application #
3300252
Study Section
Genetics Study Section (GEN)
Project Start
1989-04-01
Project End
1994-03-31
Budget Start
1991-04-01
Budget End
1992-03-31
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
Other Domestic Higher Education
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
Garcia-Garcia, Elisa; Little, Jamie C; Kalderon, Daniel (2017) The Exon Junction Complex and Srp54 Contribute to Hedgehog Signaling via ci RNA Splicing in Drosophila melanogaster. Genetics 206:2053-2068
Zadorozny, Eva V; Little, Jamie C; Kalderon, Daniel (2015) Contributions of Costal 2-Fused interactions to Hedgehog signaling in Drosophila. Development 142:931-42
Marks, Steven A; Kalderon, Daniel (2011) Regulation of mammalian Gli proteins by Costal 2 and PKA in Drosophila reveals Hedgehog pathway conservation. Development 138:2533-42
Zhou, Qianhe; Kalderon, Daniel (2011) Hedgehog activates fused through phosphorylation to elicit a full spectrum of pathway responses. Dev Cell 20:802-14
Gleason, Julie E; Eisenmann, David M (2010) Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development. Dev Biol 348:58-66
Zhou, Qianhe; Kalderon, Daniel (2010) Costal 2 interactions with Cubitus interruptus (Ci) underlying Hedgehog-regulated Ci processing. Dev Biol 348:47-57
Vied, Cynthia; Kalderon, Daniel (2009) Hedgehog-stimulated stem cells depend on non-canonical activity of the Notch co-activator Mastermind. Development 136:2177-86
Smelkinson, Margery G; Zhou, Qianhe; Kalderon, Daniel (2007) Regulation of Ci-SCFSlimb binding, Ci proteolysis, and hedgehog pathway activity by Ci phosphorylation. Dev Cell 13:481-95
Zhou, Qianhe; Apionishev, Sergey; Kalderon, Daniel (2006) The contributions of protein kinase A and smoothened phosphorylation to hedgehog signal transduction in Drosophila melanogaster. Genetics 173:2049-62
Smelkinson, Margery G; Kalderon, Daniel (2006) Processing of the Drosophila hedgehog signaling effector Ci-155 to the repressor Ci-75 is mediated by direct binding to the SCF component Slimb. Curr Biol 16:110-6

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