Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM042522-02
Application #
3301136
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1989-07-01
Project End
1994-06-30
Budget Start
1990-07-01
Budget End
1991-06-30
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Westerbeck, Jason W; Machamer, Carolyn E (2015) A Coronavirus E Protein Is Present in Two Distinct Pools with Different Effects on Assembly and the Secretory Pathway. J Virol 89:9313-23
Machamer, Carolyn E (2015) The Golgi complex in stress and death. Front Neurosci 9:421
Gilbert, Catherine E; Zuckerman, David M; Currier, Pamela L et al. (2014) Three basic residues of intracellular loop 3 of the beta-1 adrenergic receptor are required for golgin-160-dependent trafficking. Int J Mol Sci 15:2929-45
Sbodio, Juan I; Paul, Bindu D; Machamer, Carolyn E et al. (2013) Golgi protein ACBD3 mediates neurotoxicity associated with Huntington's disease. Cell Rep 4:890-7
Machamer, Carolyn E (2013) Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol 140:261-9
Ruch, Travis R; Machamer, Carolyn E (2012) The coronavirus E protein: assembly and beyond. Viruses 4:363-82
Ruch, Travis R; Machamer, Carolyn E (2012) A single polar residue and distinct membrane topologies impact the function of the infectious bronchitis coronavirus E protein. PLoS Pathog 8:e1002674
Zuckerman, David M; Hicks, Stuart W; Charron, Guillaume et al. (2011) Differential regulation of two palmitoylation sites in the cytoplasmic tail of the beta1-adrenergic receptor. J Biol Chem 286:19014-23
Ruch, Travis R; Machamer, Carolyn E (2011) The hydrophobic domain of infectious bronchitis virus E protein alters the host secretory pathway and is important for release of infectious virus. J Virol 85:675-85
Cohen, Jennifer R; Lin, Lisa D; Machamer, Carolyn E (2011) Identification of a Golgi complex-targeting signal in the cytoplasmic tail of the severe acute respiratory syndrome coronavirus envelope protein. J Virol 85:5794-803

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