Cockrell, Gregory M; Kantrowitz, Evan R (2012) Metal ion involvement in the allosteric mechanism of Escherichia coli aspartate transcarbamoylase. Biochemistry 51:7128-37
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Wang, Jie; Kantrowitz, Evan R (2006) Trapping the tetrahedral intermediate in the alkaline phosphatase reaction by substitution of the active site serine with threonine. Protein Sci 15:2395-401
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Stec, Boguslaw; Holtz, Kathleen M; Wojciechowski, Cheryl L et al. (2005) Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme. Acta Crystallogr D Biol Crystallogr 61:1072-9
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Wang, Jie; Stieglitz, Kimberly A; Kantrowitz, Evan R (2005) Metal specificity is correlated with two crucial active site residues in Escherichia coli alkaline phosphatase. Biochemistry 44:8378-86
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Zappa, S; Boudrant, J; Kantrowitz, E R (2004) Pyrococcus abyssi alkaline phosphatase: the dimer is the active form. J Inorg Biochem 98:575-81
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Boulanger Jr, Robert R; Kantrowitz, Evan R (2003) Characterization of a monomeric Escherichia coli alkaline phosphatase formed upon a single amino acid substitution. J Biol Chem 278:23497-501
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Wojciechowski, Cheryl L; Kantrowitz, Evan R (2003) Glutamic acid residues as metal ligands in the active site of Escherichia coli alkaline phosphatase. Biochim Biophys Acta 1649:68-73
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Wojciechowski, Cheryl L; Cardia, James P; Kantrowitz, Evan R (2002) Alkaline phosphatase from the hyperthermophilic bacterium T. maritima requires cobalt for activity. Protein Sci 11:903-11
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Wojciechowski, Cheryl L; Kantrowitz, Evan R (2002) Altering of the metal specificity of Escherichia coli alkaline phosphatase. J Biol Chem 277:50476-81
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Hehir, M J; Murphy, J E; Kantrowitz, E R (2000) Characterization of heterodimeric alkaline phosphatases from Escherichia coli: an investigation of intragenic complementation. J Mol Biol 304:645-56
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