Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM043153-07
Application #
2181830
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1989-12-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Saint Louis University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63103

  Publications

Matuschak, George M; Nayak, Ravi; Doyle, Timothy M et al. (2010) Acute hypoxia decreases E. coli LPS-induced cytokine production and NF-kappaB activation in alveolar macrophages. Respir Physiol Neurobiol 172:63-71
Knuepfer, Mark M; Bloodgood, Tracy A; Matuschak, George M et al. (2004) Cocaine enhances susceptibility to endotoxemic shock in a subset of rats. Crit Care Med 32:175-83
Macarthur, Heather; Couri, Daniel M; Wilken, Gerald H et al. (2003) Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholamines. Crit Care Med 31:237-45
Matuschak, G M; Henry, K A; Johanns, C A et al. (2001) Liver-lung interactions following Escherichia coli bacteremic sepsis and secondary hepatic ischemia/reperfusion injury. Am J Respir Crit Care Med 163:1002-9
Ndengele, M M; Bellone, C J; Lechner, A J et al. (2000) Brief hypoxia differentially regulates LPS-induced IL-1beta and TNF-alpha gene transcription in RAW 264.7 cells. Am J Physiol Lung Cell Mol Physiol 278:L1289-96
Loftis, L L; Johanns, C A; Lechner, A J et al. (2000) Brief hypoxic stress suppresses postbacteremic NF-kappaB activation and TNF-alpha bioactivity in perfused liver. Am J Physiol Regul Integr Comp Physiol 279:R99-R108
Matuschak, G M; Munoz, C F; Johanns, C A et al. (1998) Upregulation of postbacteremic TNF-alpha and IL-1alpha gene expression by alveolar hypoxia/reoxygenation in perfused rat lungs. Am J Respir Crit Care Med 157:629-37
Lechner, A J; Velasquez, A; Knudsen, K R et al. (1998) Cholestatic liver injury increases circulating TNF-alpha and IL-6 and mortality after Escherichia coli endotoxemia. Am J Respir Crit Care Med 157:1550-8
Matuschak, G M (1997) Supranormal oxygen delivery in critical illness. New Horiz 5:233-8
Matuschak, G M; Lechner, A J (1997) The yeast to hyphal transition following hematogenous candidiasis induces shock and organ injury independent of circulating tumor necrosis factor-alpha. Crit Care Med 25:111-20

Showing the most recent 10 out of 18 publications