Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM043585-12
Application #
6625076
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Program Officer
Anderson, James J
Project Start
1989-12-01
Project End
2004-11-30
Budget Start
2002-12-01
Budget End
2003-11-30
Support Year
12
Fiscal Year
2003
Total Cost
$261,115
Indirect Cost
Name
Michigan State University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
Halder, Sabyasachi; Parrell, Daniel; Whitten, Douglas et al. (2017) Interaction of intramembrane metalloprotease SpoIVFB with substrate Pro-?K. Proc Natl Acad Sci U S A 114:E10677-E10686
Kroos, Lee (2017) Highly Signal-Responsive Gene Regulatory Network Governing Myxococcus Development. Trends Genet 33:3-15
Parrell, Daniel; Zhang, Yang; Olenic, Sandra et al. (2017) Bacillus subtilis Intramembrane Protease RasP Activity in Escherichia coli and In Vitro. J Bacteriol 199:
Zhang, Yang; Halder, Sabyasachi; Kerr, Richard A et al. (2016) Complex Formed between Intramembrane Metalloprotease SpoIVFB and Its Substrate, Pro-?K. J Biol Chem 291:10347-62
Chen, Bin; Himes, Paul; Liu, Yu et al. (2014) Structure of bacterial transcription factor SpoIIID and evidence for a novel mode of DNA binding. J Bacteriol 196:2131-42
Konovalova, Anna; Søgaard-Andersen, Lotte; Kroos, Lee (2014) Regulated proteolysis in bacterial development. FEMS Microbiol Rev 38:493-522
Zhou, Ruanbao; Chen, Kangming; Xiang, Xianling et al. (2013) Features of Pro-?K important for cleavage by SpoIVFB, an intramembrane metalloprotease. J Bacteriol 195:2793-806
Kroos, Lee; Akiyama, Yoshinori (2013) Biochemical and structural insights into intramembrane metalloprotease mechanisms. Biochim Biophys Acta 1828:2873-85
Zhang, Yang; Luethy, Paul M; Zhou, Ruanbao et al. (2013) Residues in conserved loops of intramembrane metalloprotease SpoIVFB interact with residues near the cleavage site in pro-?K. J Bacteriol 195:4936-46
Imamura, Daisuke; Kuwana, Ritsuko; Kroos, Lee et al. (2011) Substrate specificity of SpoIIGA, a signal-transducing aspartic protease in Bacilli. J Biochem 149:665-71

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