Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM045201-02S1
Application #
3304572
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1991-01-01
Project End
1995-12-31
Budget Start
1992-01-01
Budget End
1992-12-31
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Utah
Department
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Zumbrennen-Bullough, Kimberly B; Becker, Lore; Garrett, Lillian et al. (2014) Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments. PLoS One 9:e98072
Anderson, Cole P; Shen, Macy; Eisenstein, Richard S et al. (2012) Mammalian iron metabolism and its control by iron regulatory proteins. Biochim Biophys Acta 1823:1468-83
Vashisht, Ajay A; Zumbrennen, Kimberly B; Huang, Xinhua et al. (2009) Control of iron homeostasis by an iron-regulated ubiquitin ligase. Science 326:718-21
Wallander, Michelle L; Zumbrennen, Kimberly B; Rodansky, Eva S et al. (2008) Iron-independent phosphorylation of iron regulatory protein 2 regulates ferritin during the cell cycle. J Biol Chem 283:23589-98
Zumbrennen, Kimberly B; Hanson, Eric S; Leibold, Elizabeth A (2008) HOIL-1 is not required for iron-mediated IRP2 degradation in HEK293 cells. Biochim Biophys Acta 1783:246-52
Romney, S Joshua; Thacker, Colin; Leibold, Elizabeth A (2008) An iron enhancer element in the FTN-1 gene directs iron-dependent expression in Caenorhabditis elegans intestine. J Biol Chem 283:716-25
Kim, Boe-Hyun; Jun, Yong-Chul; Jin, Jae-Kwang et al. (2007) Alteration of iron regulatory proteins (IRP1 and IRP2) and ferritin in the brains of scrapie-infected mice. Neurosci Lett 422:158-63
Wallander, Michelle L; Leibold, Elizabeth A; Eisenstein, Richard S (2006) Molecular control of vertebrate iron homeostasis by iron regulatory proteins. Biochim Biophys Acta 1763:668-89
Guo, B; Yu, Y; Leibold, E A (1994) Iron regulates cytoplasmic levels of a novel iron-responsive element-binding protein without aconitase activity. J Biol Chem 269:24252-60
Leibold, E A; Guo, B (1992) Iron-dependent regulation of ferritin and transferrin receptor expression by the iron-responsive element binding protein. Annu Rev Nutr 12:345-68

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