Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM045260-06
Application #
2183034
Study Section
Special Emphasis Panel (ZRG7-SSS-3 (08))
Project Start
1991-01-01
Project End
1996-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Schulz, Craig M; Scampavia, Louis; Ruzicka, Jaromir (2002) Real-time monitoring of lactate extrusion and glucose consumption of cultured cells using a lab-on-valve system. Analyst 127:1583-8
Schulz, Craig M; Ruzicka, Jaromir (2002) Real-time determination of glucose consumption by live cells using a lab-on-valve system with an integrated microbioreactor. Analyst 127:1293-8
Wu, Chao-Hsiang; Scampavia, Louis; Ruzicka, Jaromir (2002) Microsequential injection: anion separations using 'lab-on-valve' coupled with capillary electrophoresis. Analyst 127:898-905
Carroll, Andrea D; Scampavia, Louis; Ruzicka, Jaromir (2002) Label dilution method: a novel tool for bioligand interaction studies using bead injection in the lab-on-valve format. Analyst 127:1228-32
Lahdesmaki, I; Ruzicka, J; Ivaska, A (2000) Novel flow injection methods for drug-receptor interaction studies, based on probing cell metabolism. Analyst 125:1889-95
Hodder, P S; Beeson, C; Ruzicka, J (2000) Equilibrium and kinetic measurements of muscarinic receptor antagonism on living cells using bead injection spectroscopy. Anal Chem 72:3109-15
Lahdesmaki, I; Scampavia, L D; Beeson, C et al. (1999) Detection of oxygen consumption of cultured adherent cells by bead injection spectroscopy. Anal Chem 71:5248-52
Scampavia, L D; Hodder, P S; Lahdesmaki, I et al. (1999) Automation of functional assays by flow injection fluorescence microscopy. Trends Biotechnol 17:443-7
Connors, W L; Ruzicka, J (1999) Flow injection microscopy for the study of intracellular calcium mobilization by muscarinic agonists. Anal Biochem 268:377-82
Hodder, P S; Ruzicka, J (1999) A flow injection renewable surface technique for cell-based drug discovery functional assays. Anal Chem 71:1160-6

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