Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM045873-06
Application #
2183479
Study Section
Special Emphasis Panel (ZRG7-SB (01))
Project Start
1991-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Surgery
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
(2018) The Priming Effect of C5a on Monocytes is Predominantly Mediated by the p38 MAPK Pathway. Shock 50:127
Schaeffer, Valérie; Arbabi, Saman; Garcia, Iris A et al. (2011) Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline. J Surg Res 171:769-76
Bota, Paige C S; Collie, Angela M B; Puolakkainen, Pauli et al. (2010) Biomaterial topography alters healing in vivo and monocyte/macrophage activation in vitro. J Biomed Mater Res A 95:649-57
Cuschieri, Joseph; Bulger, Eileen; Grinsell, Rebecca et al. (2008) Insulin regulates macrophage activation through activin A. Shock 29:285-90
Cuschieri, Joseph; Gourlay, David; Garcia, Iris et al. (2004) Implications of proteasome inhibition: an enhanced macrophage phenotype. Cell Immunol 227:140-7
Bulger, Eileen M; Garcia, Iris; Maier, Ronald V (2003) Induction of heme-oxygenase 1 inhibits endothelial cell activation by endotoxin and oxidant stress. Surgery 134:146-52
Bulger, Eileen M; Garcia, Iris; Maier, Ronald V (2002) Intracellular antioxidant activity is necessary to modulate the macrophage response to endotoxin. Shock 18:58-63
Bulger, Eileen M; Arbabi, Saman; Garcia, Iris et al. (2002) The macrophage response to endotoxin requires platelet activating factor. Shock 17:173-9
Bauer, G J; Arbabi, S; Garcia, I A et al. (2000) Adherence regulates macrophage signal transduction and primes tumor necrosis factor production. Shock 14:435-40