Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM046889-05
Application #
2184381
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1992-02-01
Project End
2000-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Neurosciences
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Bargiello, Thaddeus A; Oh, Seunghoon; Tang, Qingxiu et al. (2018) Gating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states. Biochim Biophys Acta Biomembr 1860:22-39
Oh, Seunghoon; Bargiello, Thaddeus A (2015) Voltage regulation of connexin channel conductance. Yonsei Med J 56:1-15
Kwon, Taekyung; Tang, Qingxiu; Bargiello, Thaddeus A (2013) Voltage-dependent gating of the Cx32*43E1 hemichannel: conformational changes at the channel entrances. J Gen Physiol 141:243-59
Kwon, Taekyung; Roux, BenoƮt; Jo, Sunhwan et al. (2012) Molecular dynamics simulations of the Cx26 hemichannel: insights into voltage-dependent loop-gating. Biophys J 102:1341-51
Kalmatsky, B D; Batir, Y; Bargiello, T A et al. (2012) Structural studies of N-terminal mutants of connexin 32 using (1)H NMR spectroscopy. Arch Biochem Biophys 526:1-8
Bargiello, Thaddeus A; Tang, Qingxiu; Oh, Seunghoon et al. (2012) Voltage-dependent conformational changes in connexin channels. Biochim Biophys Acta 1818:1807-22
Kwon, Taekyung; Harris, Andrew L; Rossi, Angelo et al. (2011) Molecular dynamics simulations of the Cx26 hemichannel: evaluation of structural models with Brownian dynamics. J Gen Physiol 138:475-93
Freidin, Mona; Asche, Samantha; Bargiello, Thaddeus A et al. (2009) Connexin 32 increases the proliferative response of Schwann cells to neuregulin-1 (Nrg1). Proc Natl Acad Sci U S A 106:3567-72
Tang, Qingxiu; Dowd, Terry L; Verselis, Vytas K et al. (2009) Conformational changes in a pore-forming region underlie voltage-dependent ""loop gating"" of an unapposed connexin hemichannel. J Gen Physiol 133:555-70
Kalmatsky, B D; Bhagan, S; Tang, Q et al. (2009) Structural studies of the N-terminus of Connexin 32 using 1H NMR spectroscopy. Arch Biochem Biophys 490:9-16

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