Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM047795-22
Application #
2185199
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1977-12-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Hua, Jianfei; Huet, Alexis; Lopez, Carlos A et al. (2017) Capsids and Genomes of Jumbo-Sized Bacteriophages Reveal the Evolutionary Reach of the HK97 Fold. MBio 8:
Tso, DanJu; Peebles, Craig L; Maurer, Joshua B et al. (2017) On the catalytic mechanism of bacteriophage HK97 capsid crosslinking. Virology 506:84-91
Hasek, Mary L; Maurer, Joshua B; Hendrix, Roger W et al. (2017) Flexible Connectors between Capsomer Subunits that Regulate Capsid Assembly. J Mol Biol 429:2474-2489
Huet, Alexis; Duda, Robert L; Hendrix, Roger W et al. (2016) Correct Assembly of the Bacteriophage T5 Procapsid Requires Both the Maturation Protease and the Portal Complex. J Mol Biol 428:165-181
Casjens, Sherwood R; Hendrix, Roger W (2015) Bacteriophage lambda: Early pioneer and still relevant. Virology 479-480:310-30
Cardone, Giovanni; Duda, Robert L; Cheng, Naiqian et al. (2014) Metastable intermediates as stepping stones on the maturation pathways of viral capsids. MBio 5:e02067
Pope, Welkin H; Jacobs-Sera, Deborah; Russell, Daniel A et al. (2014) Genomics and proteomics of mycobacteriophage patience, an accidental tourist in the Mycobacterium neighborhood. MBio 5:e02145
Xu, Jun; Hendrix, Roger W; Duda, Robert L (2014) Chaperone-protein interactions that mediate assembly of the bacteriophage lambda tail to the correct length. J Mol Biol 426:1004-18
Tso, Dan-ju; Hendrix, Roger W; Duda, Robert L (2014) Transient contacts on the exterior of the HK97 procapsid that are essential for capsid assembly. J Mol Biol 426:2112-29
Oh, Bonnie; Moyer, Crystal L; Hendrix, Roger W et al. (2014) The delta domain of the HK97 major capsid protein is essential for assembly. Virology 456-457:171-8

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