Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM047903-03
Application #
2185317
Study Section
Molecular Biology Study Section (MBY)
Project Start
1994-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brown University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
001785542
City
Providence
State
RI
Country
United States
Zip Code
02912
Cuesta, Isabel; Zaret, Kenneth S; Santisteban, Pilar (2007) The forkhead factor FoxE1 binds to the thyroperoxidase promoter during thyroid cell differentiation and modifies compacted chromatin structure. Mol Cell Biol 27:7302-14
Sekiya, Takashi; Zaret, Kenneth S (2007) Repression by Groucho/TLE/Grg proteins: genomic site recruitment generates compacted chromatin in vitro and impairs activator binding in vivo. Mol Cell 28:291-303
Cirillo, Lisa A; Zaret, Kenneth S (2007) Specific interactions of the wing domains of FOXA1 transcription factor with DNA. J Mol Biol 366:720-4
Xu, Jian; Pope, Scott D; Jazirehi, Ali R et al. (2007) Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells. Proc Natl Acad Sci U S A 104:12377-82
Holmqvist, Per-Henrik; Belikov, Sergey; Zaret, Kenneth S et al. (2005) FoxA1 binding to the MMTV LTR modulates chromatin structure and transcription. Exp Cell Res 304:593-603
Greger, James G; Katz, Richard A; Taganov, Konstantin et al. (2004) Transduction of terminally differentiated neurons by avian sarcoma virus. J Virol 78:4902-6
Chaya, Dina; Zaret, Kenneth S (2004) Sequential chromatin immunoprecipitation from animal tissues. Methods Enzymol 376:361-72
Taganov, Konstantin D; Cuesta, Isabel; Daniel, Rene et al. (2004) Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro. J Virol 78:5848-55
Cirillo, Lisa Ann; Zaret, Kenneth S (2004) Preparation of defined mononucleosomes, dinucleosomes, and nucleosome arrays in vitro and analysis of transcription factor binding. Methods Enzymol 375:131-58
Cirillo, Lisa Ann; Lin, Frank Robert; Cuesta, Isabel et al. (2002) Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. Mol Cell 9:279-89

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