Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM048123-05
Application #
2185568
Study Section
Special Emphasis Panel (ZRG3-BBCA (01))
Project Start
1992-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Jiang, Jiansen; Wang, Yaqiang; SuĊĦac, Lukas et al. (2018) Structure of Telomerase with Telomeric DNA. Cell 173:1179-1190.e13
Upton, Heather E; Chan, Henry; Feigon, Juli et al. (2017) Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes. J Biol Chem 292:217-228
Chan, Henry; Wang, Yaqiang; Feigon, Juli (2017) Progress in Human and Tetrahymena Telomerase Structure Determination. Annu Rev Biophys 46:199-225
Wang, Yaqiang; Feigon, Juli (2017) Structural biology of telomerase and its interaction at telomeres. Curr Opin Struct Biol 47:77-87
Cash, Darian D; Feigon, Juli (2017) Structure and folding of the Tetrahymena telomerase RNA pseudoknot. Nucleic Acids Res 45:482-495
Wang, Yaqiang; Yesselman, Joseph D; Zhang, Qi et al. (2016) Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to human. Proc Natl Acad Sci U S A 113:E5125-34
Feigon, Juli; Chan, Henry; Jiang, Jiansen (2016) Integrative structural biology of Tetrahymena telomerase - insights into catalytic mechanism and interaction at telomeres. FEBS J 283:2044-50
Jiang, Jiansen; Chan, Henry; Cash, Darian D et al. (2015) Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science 350:aab4070
Singh, Mahavir; Wang, Zhonghua; Cascio, Duilio et al. (2015) Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1. J Mol Biol 427:807-23
Kim, Nak-Kyoon; Zhang, Qi; Feigon, Juli (2014) Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function. Nucleic Acids Res 42:3395-408

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