Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM048610-04
Application #
2186109
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1993-01-01
Project End
1996-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Samuels, Stuart E; Lipitz, Jeffrey B; Wang, Junjie et al. (2013) Arachidonic acid closes innexin/pannexin channels and thereby inhibits microglia cell movement to a nerve injury. Dev Neurobiol 73:621-31
Dahl, Gerhard; Qiu, Feng; Wang, Junjie (2013) The bizarre pharmacology of the ATP release channel pannexin1. Neuropharmacology 75:583-93
Dahl, Gerhard; Keane, Robert W (2012) Pannexin: from discovery to bedside in 11±4 years? Brain Res 1487:150-9
Qiu, Feng; Wang, Junjie; Spray, David C et al. (2011) Two non-vesicular ATP release pathways in the mouse erythrocyte membrane. FEBS Lett 585:3430-5
Ambrosi, Cinzia; Gassmann, Oliver; Pranskevich, Jennifer N et al. (2010) Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other. J Biol Chem 285:24420-31
Samuels, Stuart E; Lipitz, Jeffrey B; Dahl, Gerhard et al. (2010) Neuroglial ATP release through innexin channels controls microglial cell movement to a nerve injury. J Gen Physiol 136:425-42
Wang, Junjie; Dahl, Gerhard (2010) SCAM analysis of Panx1 suggests a peculiar pore structure. J Gen Physiol 136:515-27
Qiu, Feng; Dahl, Gerhard (2009) A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP. Am J Physiol Cell Physiol 296:C250-5
Bunse, Stefanie; Locovei, Silviu; Schmidt, Matthias et al. (2009) The potassium channel subunit Kvbeta3 interacts with pannexin 1 and attenuates its sensitivity to changes in redox potentials. FEBS J 276:6258-70
Ransford, George A; Fregien, Nevis; Qiu, Feng et al. (2009) Pannexin 1 contributes to ATP release in airway epithelia. Am J Respir Cell Mol Biol 41:525-34

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