Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM049046-04
Application #
2186572
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1993-05-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rockefeller University
Department
Type
Organized Research Units
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
Kibe, Tatsuya; Zimmermann, Michal; de Lange, Titia (2016) TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres. Mol Cell 61:236-46
Doksani, Ylli; Wu, John Y; de Lange, Titia et al. (2013) Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation. Cell 155:345-356
Ahmed, Emad A; Sfeir, Agnel; Takai, Hiroyuki et al. (2013) Ku70 and non-homologous end joining protect testicular cells from DNA damage. J Cell Sci 126:3095-104
Lovejoy, Courtney A; Li, Wendi; Reisenweber, Steven et al. (2012) Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet 8:e1002772
Sfeir, Agnel; de Lange, Titia (2012) Removal of shelterin reveals the telomere end-protection problem. Science 336:593-7
Takai, Kaori K; Kibe, Tatsuya; Donigian, Jill R et al. (2011) Telomere protection by TPP1/POT1 requires tethering to TIN2. Mol Cell 44:647-59
Scherthan, Harry; Sfeir, Agnel; de Lange, Titia (2011) Rap1-independent telomere attachment and bouquet formation in mammalian meiosis. Chromosoma 120:151-7
Davoli, Teresa; de Lange, Titia (2011) The causes and consequences of polyploidy in normal development and cancer. Annu Rev Cell Dev Biol 27:585-610
Kibe, Tatsuya; Osawa, Gail A; Keegan, Catherine E et al. (2010) Telomere protection by TPP1 is mediated by POT1a and POT1b. Mol Cell Biol 30:1059-66
Wu, Peng; van Overbeek, Megan; Rooney, Sean et al. (2010) Apollo contributes to G overhang maintenance and protects leading-end telomeres. Mol Cell 39:606-17

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