Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM049351-04
Application #
2186945
Study Section
Molecular Biology Study Section (MBY)
Project Start
1993-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Pehrson, John R; Changolkar, Lakshmi N; Costanzi, Carl et al. (2014) Mice without macroH2A histone variants. Mol Cell Biol 34:4523-33
Gaspar-Maia, Alexandre; Qadeer, Zulekha A; Hasson, Dan et al. (2013) MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Nat Commun 4:1565
Baudino, Lucie; Changolkar, Lakshmi N; Pehrson, John R et al. (2010) The Sgp3 locus derived from the 129 strain is responsible for enhanced endogenous retroviral expression in macroH2A1-deficient mice. J Autoimmun 35:398-403
Changolkar, Lakshmi N; Singh, Geetika; Cui, Kairong et al. (2010) Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin. Mol Cell Biol 30:5473-83
Bernstein, Emily; Muratore-Schroeder, Tara L; Diaz, Robert L et al. (2008) A phosphorylated subpopulation of the histone variant macroH2A1 is excluded from the inactive X chromosome and enriched during mitosis. Proc Natl Acad Sci U S A 105:1533-8
Changolkar, Lakshmi N; Singh, Geetika; Pehrson, John R (2008) macroH2A1-dependent silencing of endogenous murine leukemia viruses. Mol Cell Biol 28:2059-65