Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM049850-01A1
Application #
2187393
Study Section
Genetics Study Section (GEN)
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Wang, Liangjun; Joshi, Preeti; Miller, Ellen L et al. (2018) A Role for Monomethylation of Histone H3-K27 in Gene Activity in Drosophila. Genetics 208:1023-1036
Herzog, Veronika A; Lempradl, Adelheid; Trupke, Johanna et al. (2014) A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element. Nat Genet 46:973-981
Simon, Jeffrey A; Kingston, Robert E (2013) Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Mol Cell 49:808-24
Rai, Aswathy N; Vargas, Marcus L; Wang, Liangjun et al. (2013) Elements of the polycomb repressor SU(Z)12 needed for histone H3-K27 methylation, the interface with E(Z), and in vivo function. Mol Cell Biol 33:4844-56
O'Meara, M Maggie; Simon, Jeffrey A (2012) Inner workings and regulatory inputs that control Polycomb repressive complex 2. Chromosoma 121:221-34
Smith, Matthew; Mallin, Daniel R; Simon, Jeffrey A et al. (2011) Small ubiquitin-like modifier (SUMO) conjugation impedes transcriptional silencing by the polycomb group repressor Sex Comb on Midleg. J Biol Chem 286:11391-400
Wang, Liangjun; Jahren, Neal; Miller, Ellen L et al. (2010) Comparative analysis of chromatin binding by Sex Comb on Midleg (SCM) and other polycomb group repressors at a Drosophila Hox gene. Mol Cell Biol 30:2584-93
Chen, Shuai; Bohrer, Laura R; Rai, Aswathy N et al. (2010) Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2. Nat Cell Biol 12:1108-14
Zhu, Changqi C; Bornemann, Douglas J; Zhitomirsky, David et al. (2008) Drosophila histone deacetylase-3 controls imaginal disc size through suppression of apoptosis. PLoS Genet 4:e1000009
Wang, Liangjun; Jahren, Neal; Vargas, Marcus L et al. (2006) Alternative ESC and ESC-like subunits of a polycomb group histone methyltransferase complex are differentially deployed during Drosophila development. Mol Cell Biol 26:2637-47

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