Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050231-02
Application #
2187916
Study Section
Molecular Biology Study Section (MBY)
Project Start
1995-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Chetverina, Darya; Fujioka, Miki; Erokhin, Maksim et al. (2017) Boundaries of loop domains (insulators): Determinants of chromosome form and function in multicellular eukaryotes. Bioessays 39:
Peacock, Jacob; Jaynes, James B (2017) Using competition assays to quantitatively model cooperative binding by transcription factors and other ligands. Biochim Biophys Acta Gen Subj 1861:2789-2801
Fujioka, Miki; Mistry, Hemlata; Schedl, Paul et al. (2016) Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans. PLoS Genet 12:e1005889
Lacin, Haluk; Rusch, Jannette; Yeh, Raymond T et al. (2014) Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of nitric oxide synthase and Fd59a/Fox-D. Dev Biol 388:117-33
Fujioka, Miki; Sun, Guizhi; Jaynes, James B (2013) The Drosophila eve insulator Homie promotes eve expression and protects the adjacent gene from repression by polycomb spreading. PLoS Genet 9:e1003883
Fujioka, Miki; Jaynes, James B (2012) Regulation of a duplicated locus: Drosophila sloppy paired is replete with functionally overlapping enhancers. Dev Biol 362:309-19
Fujioka, Miki; Gebelein, Brian; Cofer, Zenobia C et al. (2012) Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired. Dev Biol 366:382-92
Johnston, Danika M; Sedkov, Yurii; Petruk, Svetlana et al. (2011) Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development. Mol Cell 44:51-61
Prazak, Lisa; Fujioka, Miki; Gergen, J Peter (2010) Non-additive interactions involving two distinct elements mediate sloppy-paired regulation by pair-rule transcription factors. Dev Biol 344:1048-59
Fujioka, Miki; Wu, Xian; Jaynes, James B (2009) A chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication. Development 136:3077-87

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