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Whitley, Matthew J; Arjunan, Palaniappa; Nemeria, Natalia S et al. (2018) Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the ?V138M variant of human pyruvate dehydrogenase. J Biol Chem 293:13204-13213
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Guevara, Elena L; Yang, Luying; Birkaya, Barbara et al. (2017) Global view of cognate kinase activation by the human pyruvate dehydrogenase complex. Sci Rep 7:42760
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Ambrus, Attila; Nemeria, Natalia S; Torocsik, Beata et al. (2015) Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components. Free Radic Biol Med 89:642-50
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Nemeria, Natalia S; Ambrus, Attila; Patel, Hetalben et al. (2014) Human 2-oxoglutarate dehydrogenase complex E1 component forms a thiamin-derived radical by aerobic oxidation of the enamine intermediate. J Biol Chem 289:29859-73
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Basta, Leighanne A Brammer; Patel, Hetalben; Kakalis, Lazaros et al. (2014) Defining critical residues for substrate binding to 1-deoxy-D-xylulose 5-phosphate synthase--active site substitutions stabilize the predecarboxylation intermediate C2?-lactylthiamin diphosphate. FEBS J 281:2820-2837
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Wang, Junjie; Nemeria, Natalia S; Chandrasekhar, Krishnamoorthy et al. (2014) Structure and function of the catalytic domain of the dihydrolipoyl acetyltransferase component in Escherichia coli pyruvate dehydrogenase complex. J Biol Chem 289:15215-30
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Arjunan, Palaniappa; Wang, Junjie; Nemeria, Natalia S et al. (2014) Novel binding motif and new flexibility revealed by structural analyses of a pyruvate dehydrogenase-dihydrolipoyl acetyltransferase subcomplex from the Escherichia coli pyruvate dehydrogenase multienzyme complex. J Biol Chem 289:30161-76
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Patel, Mulchand S; Nemeria, Natalia S; Furey, William et al. (2014) The pyruvate dehydrogenase complexes: structure-based function and regulation. J Biol Chem 289:16615-23
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Patel, Hetalben; Shim, Da Jeong; Farinas, Edgardo T et al. (2013) Investigation of the donor and acceptor range for chiral carboligation catalyzed by the E1 component of the 2-oxoglutarate dehydrogenase complex. J Mol Catal B Enzym 98:
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Kumaran, Sowmini; Patel, Mulchand S; Jordan, Frank (2013) Nuclear magnetic resonance approaches in the study of 2-oxo acid dehydrogenase multienzyme complexes--a literature review. Molecules 18:11873-903
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Showing the most recent 10 out of 28 publications
