Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050740-02
Application #
2188776
Study Section
Experimental Virology Study Section (EVR)
Project Start
1995-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Cornell University
Department
Microbiology/Immun/Virology
Type
Schools of Veterinary Medicine
DUNS #
City
Ithaca
State
NY
Country
United States
Zip Code
14850

  Publications

Mbong, Ekaette F; Woodley, Lucille; Frost, Elizabeth et al. (2012) Deletion of UL21 causes a delay in the early stages of the herpes simplex virus 1 replication cycle. J Virol 86:7003-7
Yang, Kui; Wills, Elizabeth G; Baines, Joel D (2012) Release of the herpes simplex virus 1 protease by self cleavage is required for proper conformation of the portal vertex. Virology 429:63-73
Johnson, David C; Baines, Joel D (2011) Herpesviruses remodel host membranes for virus egress. Nat Rev Microbiol 9:382-94
Yang, Kui; Baines, Joel D (2009) Tryptophan residues in the portal protein of herpes simplex virus 1 critical to the interaction with scaffold proteins and incorporation of the portal into capsids. J Virol 83:11726-33
Scholtes, Luella; Baines, Joel D (2009) Effects of major capsid proteins, capsid assembly, and DNA cleavage/packaging on the pUL17/pUL25 complex of herpes simplex virus 1. J Virol 83:12725-37
Duffy, Carol; Mbong, Ekaette F; Baines, Joel D (2009) VP22 of herpes simplex virus 1 promotes protein synthesis at late times in infection and accumulation of a subset of viral mRNAs at early times in infection. J Virol 83:1009-17
Yang, Kui; Baines, Joel D (2008) Domain within herpes simplex virus 1 scaffold proteins required for interaction with portal protein in infected cells and incorporation of the portal vertex into capsids. J Virol 82:5021-30
Yang, Kui; Homa, Fred; Baines, Joel D (2007) Putative terminase subunits of herpes simplex virus 1 form a complex in the cytoplasm and interact with portal protein in the nucleus. J Virol 81:6419-33
Wills, Elizabeth; Scholtes, Luella; Baines, Joel D (2006) Herpes simplex virus 1 DNA packaging proteins encoded by UL6, UL15, UL17, UL28, and UL33 are located on the external surface of the viral capsid. J Virol 80:10894-9
Duffy, Carol; Lavail, Jennifer H; Tauscher, Andrew N et al. (2006) Characterization of a UL49-null mutant: VP22 of herpes simplex virus type 1 facilitates viral spread in cultured cells and the mouse cornea. J Virol 80:8664-75

Showing the most recent 10 out of 25 publications