Molecular Mechanisms of Signal Tranduction by Chey

Bourret, Robert B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 5R01GM050860-03
• Application #: 2188998
• Study Section: Microbial Physiology and Genetics Subcommittee 2 (MBC)
• Project Start: 1994-05-01
• Project End: 1999-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of North Carolina Chapel Hill
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• DUNS #: 078861598
• City: Chapel Hill
• State: NC
• Country: United States
• Zip Code: 27599

Publications

Silversmith, Ruth E; Bourret, Robert B (2018) Fluorescence Measurement of Kinetics of CheY Autophosphorylation with Small Molecule Phosphodonors. Methods Mol Biol 1729:321-335

Bourret, Robert B (2017) Learning from Adversity? J Bacteriol 199:

Silversmith, Ruth E; Wang, Boya; Fulcher, Nanette B et al. (2016) Phosphoryl Group Flow within the Pseudomonas aeruginosa Pil-Chp Chemosensory System: DIFFERENTIAL FUNCTION OF THE EIGHT PHOSPHOTRANSFERASE AND THREE RECEIVER DOMAINS. J Biol Chem 291:17677-91

Page, Stephani C; Immormino, Robert M; Miller, Thane H et al. (2016) Experimental Analysis of Functional Variation within Protein Families: Receiver Domain Autodephosphorylation Kinetics. J Bacteriol 198:2483-93

Immormino, Robert M; Silversmith, Ruth E; Bourret, Robert B (2016) A Variable Active Site Residue Influences the Kinetics of Response Regulator Phosphorylation and Dephosphorylation. Biochemistry 55:5595-5609

Page, Stephani C; Silversmith, Ruth E; Collins, Edward J et al. (2015) Imidazole as a Small Molecule Analogue in Two-Component Signal Transduction. Biochemistry 54:7248-60

Immormino, Robert M; Starbird, Chrystal A; Silversmith, Ruth E et al. (2015) Probing Mechanistic Similarities between Response Regulator Signaling Proteins and Haloacid Dehalogenase Phosphatases. Biochemistry 54:3514-27

Creager-Allen, Rachel L; Silversmith, Ruth E; Bourret, Robert B (2013) A link between dimerization and autophosphorylation of the response regulator PhoB. J Biol Chem 288:21755-69

Thomas, Stephanie A; Immormino, Robert M; Bourret, Robert B et al. (2013) Nonconserved active site residues modulate CheY autophosphorylation kinetics and phosphodonor preference. Biochemistry 52:2262-73

Freeman, Ashalla M; Mole, Beth M; Silversmith, Ruth E et al. (2011) Action at a distance: amino acid substitutions that affect binding of the phosphorylated CheY response regulator and catalysis of dephosphorylation can be far from the CheZ phosphatase active site. J Bacteriol 193:4709-18