Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM052493-02
Application #
2191542
Study Section
Radiation Study Section (RAD)
Project Start
1995-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Lieberman, Howard B (2006) Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity. J Cell Biochem 97:690-7
Pandita, Raj K; Sharma, Girdhar G; Laszlo, Andrei et al. (2006) Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair. Mol Cell Biol 26:1850-64
Zhou, Hongning; Ivanov, Vladimir N; Gillespie, Joseph et al. (2005) Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathway. Proc Natl Acad Sci U S A 102:14641-6
Karnitz, Larry M; Flatten, Karen S; Wagner, Jill M et al. (2005) Gemcitabine-induced activation of checkpoint signaling pathways that affect tumor cell survival. Mol Pharmacol 68:1636-44
Smilenov, Lubomir B; Lieberman, Howard B; Mitchell, Stephen A et al. (2005) Combined haploinsufficiency for ATM and RAD9 as a factor in cell transformation, apoptosis, and DNA lesion repair dynamics. Cancer Res 65:933-8
Zhu, Aiping; Zhou, Hongning; Leloup, Corinne et al. (2005) Differential impact of mouse Rad9 deletion on ionizing radiation-induced bystander effects. Radiat Res 164:655-61
Hopkins, Kevin M; Auerbach, Wojtek; Wang, Xiang Yuan et al. (2004) Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality. Mol Cell Biol 24:7235-48
Loegering, David; Arlander, Sonnet J H; Hackbarth, Jennifer et al. (2004) Rad9 protects cells from topoisomerase poison-induced cell death. J Biol Chem 279:18641-7
Yin, Yuxin; Zhu, Aiping; Jin, Yan J et al. (2004) Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21. Proc Natl Acad Sci U S A 101:8864-9
Lieberman, Howard B; Hopkins, Kevin M (2004) Methods to induce cell cycle checkpoints. Methods Mol Biol 241:3-10

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