Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM052717-01A1
Application #
2191844
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1996-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Petrova, Yuliya I; Spano, MarthaJoy M; Gumbiner, Barry M (2012) Conformational epitopes at cadherin calcium-binding sites and p120-catenin phosphorylation regulate cell adhesion. Mol Biol Cell 23:2092-108
Yoder, Michael D; Gumbiner, Barry M (2011) Axial protocadherin (AXPC) regulates cell fate during notochordal morphogenesis. Dev Dyn 240:2495-504
Chen, Xuejun; Koh, Eunjin; Yoder, Michael et al. (2009) A protocadherin-cadherin-FLRT3 complex controls cell adhesion and morphogenesis. PLoS One 4:e8411
Chen, Xuejun; Molino, Caitlyn; Liu, Li et al. (2007) Structural elements necessary for oligomerization, trafficking, and cell sorting function of paraxial protocadherin. J Biol Chem 282:32128-37
Tsuiji, Hitomi; Xu, Liang; Schwartz, Kathleen et al. (2007) Cadherin conformations associated with dimerization and adhesion. J Biol Chem 282:12871-82
Chen, Xuejun; Gumbiner, Barry M (2006) Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity. J Cell Biol 174:301-13
Chen, Xuejun; Gumbiner, Barry M (2006) Crosstalk between different adhesion molecules. Curr Opin Cell Biol 18:572-8
Zhu, B; Chappuis-Flament, S; Wong, E et al. (2003) Functional analysis of the structural basis of homophilic cadherin adhesion. Biophys J 84:4033-42
Boggon, Titus J; Murray, John; Chappuis-Flament, Sophie et al. (2002) C-cadherin ectodomain structure and implications for cell adhesion mechanisms. Science 296:1308-13
Huen, Arthur C; Park, Jung K; Godsel, Lisa M et al. (2002) Intermediate filament-membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength. J Cell Biol 159:1005-17

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